Identification of BLAD and citrullinemia carriers in Chinese Holstein cattle
Journal Title: Animal Science Papers and Reports - Year 2011, Vol 29, Issue 1
Abstract
Bovine leukocyte adhesion deficiency (BLAD) and citrullinemia are two autosomal recessive genetic diseases in Holstein cattle and both result in death of homozygous animals. Through the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technology and DNA sequencing, one citrullinemia and three BLAD carriers were found in a population of 615 Chinese Holstein cattle, including 436 cows and 179 bulls. Citrullinemia and BLAD carrier frequency was 0.16% and 0.49%, respectively, in tested Chinese Holstein cattle. In this study, the first citrullinemia carrier occurring in Chinese Holstein cattle is described, although the world frequency of this disorder is very low.
Authors and Affiliations
Jianbin Li, Hongmei Wang, Yi Zhang, Minghai Hou, Jifeng Zhong, Yuan Zhang
Keywords
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