Insulin use in transplant patients
Journal Title: Journal of the Indian Medical Association - Year 2018, Vol 116, Issue 8
Abstract
India is the preferred destination for organ transplant in South-East Asia. Tacrolimus and Prednisolone are commonly used in the immunosuppressive regimens after transplant to prevent allograft rejection. Both of these agents potentially cause hyperglycemia leading to Post-transplantation diabetes mellitus (PTDM). Management of PTDM is a clinical challenge because it is required to achieve pristine glycemic control to avoid complications. Insulin is the preferred agent for management of PTDM both in cases of patients having pre-existing diabetes mellitus and new onset of diabetes posttransplantation (NODAT). The review focusses on use of insulin in post-transplant patient with special focus on newer ‘smart’ insulin protocols which can optimize glycemic management
Authors and Affiliations
Om J Lakhani, Hardik Kotecha
Keywords
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