Invasive candidiasis outbreak in a neonatal intensive care unit (NICU), a descriptive study from tertiary care teaching hospital of western part of Maharashtra

Journal Title: Medpulse International Journal of Microbiology - Year 2019, Vol 9, Issue 2

Abstract

Background: Candidemia outbreaks are frequent event take place in NICU accounting about 9-13%. Especially non-albicans Candida species emerged as an important cause of various outbreaks in NICU. There are various predisposing factors which may be a culprit for an outbreak. Early on detection and source of infection is helpful in effective management of candidemia outbreak. Material and methods: There was remarkable increase in number of candida isolates from blood cultures in Microbiology laboratory. Different laboratory procedures were performed to identify these isolates till species level and also antifungal susceptibility test was done further. Environmental samples were collected from NICU to trace the cause of outbreak. Results: Candidemia incidence in current outbreak was 7.71%. The most common species involved was C.glabrata in 43(81.13%) followed by C.tropicalis 10(18.87%). Among environmental samples these isolates were isolated from in use Total Parenteral Nutrition (TPN) and Dextrose solution used in NICU. Conclusion: NICU is always vulnerable unit where standard safety precautions should be at utmost level. Any minor breach in practices can lead to major events. Therefore, if needed surveillance should be done to evaluate source of infection before time and also for effective management of such events.

Authors and Affiliations

Shilpa Putta, Neeta Jangale, Sushma Pednekar, Vijay Kulkarni, Aparajeet Walawalkar

Keywords

Related Articles

Hereditary angioedema and gastrointestinal complications: Case report

Background: Hereditary angioedema (HAE) caused by C1-esterase inhibitor(C1-INH) deficiency is an autosomal dominant disease resulting from mutation in the C1-inhibitor gene. In classic HAE, abdominal attacks are mostly c...

Comparison of immunochromatogenic method of antigen detection and Giemsa staining with polymerase chain reaction (PCR) for detection of chlamydia trachomatis infection in infertile women

Context: Chlamydial infection is a silent epidemic. The varied prevalence of chlamydial infection in India, leads to an urgent need to look for simple, inexpensive and sensitive tests for early diagnosis. Aims: To determ...

Increased prevalence of MDR non fermenters group of bacteria recovered from nosocomial infections in tertiary care hospital, East Midnapur, West Bengal

Aim of study: To evaluate the incidence rate of Non-fermenters group of bacteria along with their multidrug resistant pattern. Materials and methods: A retrospective cross-sectional study was undertaken to assess the fre...

Study of an outbreak of respiratory diphtheria in local community,Kakinada

Objectives:1. Isolation, speciation and toxigenicity testing of Corynebacterium diphtheria. 2. To study the epidemiology, clinical features, complications and outcomes in respiratory diphtheria.Materials and Methods: 31...

ESKAPE pathogens: Trends in antibiotic resistance pattern

Background: Trend in resistance pattern of ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter, Pseudomonas aeruginosa, and Enterobacter/E.coli species) pathogens and their prevailin...

Download PDF file
  • EP ID EP486249
  • DOI 10.26611/1008921
  • Views 59
  • Downloads 0

How To Cite

Shilpa Putta, Neeta Jangale, Sushma Pednekar, Vijay Kulkarni, Aparajeet Walawalkar (2019). Invasive candidiasis outbreak in a neonatal intensive care unit (NICU), a descriptive study from tertiary care teaching hospital of western part of Maharashtra. Medpulse International Journal of Microbiology, 9(2), 9-12. https://europub.co.uk/articles/-A-486249