Invasive candidiasis outbreak in a neonatal intensive care unit (NICU), a descriptive study from tertiary care teaching hospital of western part of Maharashtra
Journal Title: Medpulse International Journal of Microbiology - Year 2019, Vol 9, Issue 2
Abstract
Background: Candidemia outbreaks are frequent event take place in NICU accounting about 9-13%. Especially non-albicans Candida species emerged as an important cause of various outbreaks in NICU. There are various predisposing factors which may be a culprit for an outbreak. Early on detection and source of infection is helpful in effective management of candidemia outbreak. Material and methods: There was remarkable increase in number of candida isolates from blood cultures in Microbiology laboratory. Different laboratory procedures were performed to identify these isolates till species level and also antifungal susceptibility test was done further. Environmental samples were collected from NICU to trace the cause of outbreak. Results: Candidemia incidence in current outbreak was 7.71%. The most common species involved was C.glabrata in 43(81.13%) followed by C.tropicalis 10(18.87%). Among environmental samples these isolates were isolated from in use Total Parenteral Nutrition (TPN) and Dextrose solution used in NICU. Conclusion: NICU is always vulnerable unit where standard safety precautions should be at utmost level. Any minor breach in practices can lead to major events. Therefore, if needed surveillance should be done to evaluate source of infection before time and also for effective management of such events.
Authors and Affiliations
Shilpa Putta, Neeta Jangale, Sushma Pednekar, Vijay Kulkarni, Aparajeet Walawalkar
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