Investigation of a suspected outbreak of carbapenem-resistant Klebsiella pneumonia infection
Journal Title: Shanghai Journal of Preventive Medicine - Year 2023, Vol 35, Issue 2
Abstract
ObjectiveTo investigate a suspected outbreak of healthcare-associated infection ï¼HAIï¼ caused by carbapenem-resistant Klebsiella pneumonia ï¼CRKPï¼ in a secondary grade-A hospitalï¼ analyze the infection source and transmission routeï¼ and put forward corresponding preventive and control measures.MethodsEpidemiological investigation was conducted on 5 patients with CRKP infection in department of neurosurgery during December 23â30ï¼ 2021. Specimens were collected with the environmental microbiology monitoring procedure. CRKP isolated from the environmental samples were analyzed by multilocus sequence typing ï¼MLSTï¼ method. Comprehensive measures were taken to control the CRKP infection.ResultsThe 5 infected patients were located in 3 roomsï¼ and all were diagnosed as HAI. The antimicrobial susceptibility testing results from the specimens of 3 CRKP infected patients were the same. Through environmental microbiology monitoringï¼ CRKP strains were detected from the faucet handle and sink specimens in 3 rooms. The results of MLST analysis showed that the faucet handle and sink specimens in room 2 and 3 were ST11 type. The environmental specimen in room 1 was ST23 type. The suspected outbreak was effectively controlled after comprehensive interventions.ConclusionHAI suspected outbreak might be caused by the environmental contamination from the pathogens of CRKP-infected patients as well as the contaminated hands of medical staff and accompanying family members. Strengthening the publicityï¼ education and management of medical staff and accompanying staffï¼ early identification of infection outbreaksï¼ and timely comprehensive control measures are the keys to controlling multidrug-resistant nosocomial infection outbreaks.
Authors and Affiliations
ZHU Wen,LIANG Yi,WENG Chao,
Keywords
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