Iron Deficiency Anemia In Pregnancy: Pre And Post Iron Sucrose Therapy In A Tertiary Referral Centre
Journal Title: IOSR Journal of Biotechnology and Biochemistry (IOSR-JBB - Year 2018, Vol 4, Issue 1
Abstract
Introduction: Iron deficiency is commonly prevalent in women of reproductive age group.Early detection of iron stores before the development of anemia is beneficial. The maternal iron level is important for the growth of fetus and is always advantageous to have parameters which can detect iron deficiency at an early stage. The timely implementation of intervention to correct maternal iron status will improve the fetal outcome. Objectives: To study levels of serum transferrin, iron and serum ferritin during pregnancy,pre and post intravenous Iron sucrose therapy in iron deficiency anemia. Materials and Methods: Case control study was conducted on 60 pregnant women reporting to antenatal clinic between 18-34 weeks gestational age.Samples were collected and analysedfrom diagnosed cases of Iron deficiency anemia for Serum Iron, Ferritin and Transferrin before and after intravenous iron sucrose therapyand were compared with that of normal pregnant ladies. Result:. The hemogobin levels were 11.97±1.09% in controls and 8.21±1.1% and 10.64±1.5% in cases on Day 1 and day 28. The Serum iron was 133.83±32.4µg/dl in controls and 20.66±10.01µg/dl and 79.97±40.32µg/dl in cases on day 1 and 28. Similarly serum ferritin was 35.6±7.85 µg/L, 13.25±10.7 µg/L and 40.2±62 µg/Lrespectively in normal pregenant women and iron deficient women pre and post iron sucrose therapy. The serum transferrin in contrlos was 271.31±35.13mg/dl and in cases were 471.05±70.6mg/dl on day 1 and 427.6±83.51mg/dl on day 28. All were statistically significant. Conclusion: The finding of the present study suggests that serum iron, ferritin and transferrin levels measurement could be a better parameter for predicting iron deficiency in pregnancy and can be advised along with other routine hematological investigations.
Authors and Affiliations
Dr. Anitha Mukthapuram, Dr. Sujata Maitra, Dr. Gopalakrishna Huligol, Dr. Sreelatha, Dr. Vishwanath H. L
Keywords
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