ISOLATION OF Α-GLUCOSIDASE INHIBITORY ACTIVE COMPOUNDS FROM ETHANOL EXTRACT OF KAYU TUAH (ANTIDESMA CELEBICUM MIQ.) LEAVES  

Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2015, Vol 6, Issue 1

Abstract

Antidesma celebicum Miq. belongs to Euphorbiaceae family has been used as antidiabetic traditional medicine. The aim of the research was to isolate the α-Glucosidase inhibitory compound from ethanol extract of Antidesma celebicum leaves. The isolation have been done using column chromatography silica gel 60 and the structure was determinated base on spectral data of IR, MS, NMR. The result showed that the isolation obtained gallic acid as α-Glucosidase inhibitor with IC50 value of 0.057 mM. 

Authors and Affiliations

Fajar Novi , Elya Berna , Katrin

Keywords

Related Articles

CLINICAL EVALUATION OF KODIPAVALA CHUNNAM IN THE TREATMENT OF INFECTIVE HEPATITIS, DRUG INDUCED HEPATITIS AND ALCOHOLIC HEPATITIS 

The present clinical study was carried out to validate the efficacy and safety of Siddha Herbo- mineral formulation ‘Kodipavala Chunnam’ in the treatment of Infective hepatitis, Drug induced hepatitis and Alcoholic hepat...

ENHANCEMENT OF SOLUBILITY AND DISSOLUTION RATE OF CURCUMIN BY SOLID DISPERSION TECHNIQUE  

Curcumin, a naturally occurring highly lipophilic molecule has wide range of pharmacological activities. However, its limitedaqueous solubility and degradation at alkaline pH restricts its bioavailability. Solid dispersi...

A HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC ASSAY FOR NICORANDIL IN BULK DRUG AND ITS PHARMACEUTICAL DOSAGE FORMS 

A simple, rapid and reproducible high performance reverse phase liquid chromatographic method has been developed for quantitative estimation of Nicorandil in rotacap using a, C18 column and UV detection at 254nm. The iso...

PHYTOCHEMICAL INVESTIGATION AND ANTHELMINTIC ACTIVITY OF CELOSIA CRISTATA LEAF EXTRACTS  

Development of anthelmintics from medicinal plants might be served as an alternative source for the conventional anthelmintic drugs. The present study was attempted to assess the possible anthelmintic activity for chloro...

FORMULATION AND EVALUATION OF GASTRO RETENTIVE DRUG DELIVERY SYSTEM OF STAVUDINE 

The present study was designed to formulate and evaluate hydro dynamically balanced Floating Drug Delivery Systems as controlled release modules, which prolongs the release rate of the drugs. Stavudine is an anti- retrov...

Download PDF file
  • EP ID EP158288
  • DOI 10.7897/2230-8407.0615
  • Views 113
  • Downloads 0

How To Cite

Fajar Novi, Elya Berna, Katrin (2015). ISOLATION OF Α-GLUCOSIDASE INHIBITORY ACTIVE COMPOUNDS FROM ETHANOL EXTRACT OF KAYU TUAH (ANTIDESMA CELEBICUM MIQ.) LEAVES  . International Research Journal of Pharmacy (IRJP), 6(1), 22-24. https://europub.co.uk/articles/-A-158288