Metabolism of retinyl esters in humans after ingestion of retinol
Journal Title: Journal of Analytical Bio-Science - Year 2012, Vol 35, Issue 2
Abstract
Using high-performance liquid chromatography, we determined which retinyl esters predominately circulate in human serum after the ingestion of rapeseed oil and a few drops of retinyl palmitate. Fatty acids, predominately as palmitic acid followed by oleic, linoleic, and stearic acids, as well as retinyl esters, predominately as retinyl palmitate followed by retinyl stearate, oleate and linoleate, increased in serum after the ingestion of rapeseed oil and a few drops of retinyl palmitate. Re-esterification ratios (molar ratios between the concentrations of fatty acids and the corresponding retinyl esters recovered in serum after the ingestion of rapeseed oil and a retinyl palmitate) were markedly increased in saturated fatty acids (palmitic and stearic acids). Re-esterification ratios of unsaturated fatty acids (oleic and linoleic acids) were low compared with saturated fatty acids.
Authors and Affiliations
Hiroshi Ihara
Keywords
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