MICROEMULSIFYING DRUG DELIVERY SYSTEM-NEW ERA OF DRUG DELIVERY SYSTEM
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2013, Vol 1, Issue 1
Abstract
Micro emulsions are isotropic, thermodynamically stable transparent system of oil, water and surfactant, frequently in combination with a co-surfactant. These versatile systems are currently of great technological and scientific interest to the researchers because of their potential to incorporate a wide range of drug molecules (hydrophilic and hydrophobic) due to the presence of both lipophilic and hydrophilic domains. They have been used to improve the oral bioavailability of various poorly soluble drugs.The discoveries of micro emulsions have attained increasing significance both in basic research and in industry. Due to their unique properties namely ultralow interfacial tension, large interfacial area, thermodynamic stability and the ability to solubilise other immiscible liquids, uses and applications of micro emulsions have been numerous. In topical formulations they have been proved to increase the cutaneous absorption of both lipophilic and hydrophilic API’s. In this type of applications the micro emulsions attribute to the performance to generally a higher solubility of the API’S of micro emulsions, generating increased concentration gradient towards skin.
Authors and Affiliations
Debjit Bhowmik,Harish G, S. Duraivel, Aravind. G, KP Sampath Kumar
Keywords
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