Multiple Sclerosis Under Attack; Shehata’s Therapy
Journal Title: Turkish Journal of Immunology - Year 2018, Vol 6, Issue 1
Abstract
Multiple sclerosis is an autoimmune disease characterized by inflammatory demylination of the nerves in the central nervous system (brain and spinal cord). Depending on the attacked sites, the disease manifestations vary from limited sensory and/or motoric deficits to wide spread neurological and cognitive deficits. Similar to other autoimmune neurological and non-neurological diseases, the available therapeutic strategies rely on the pharmacological modulation of the immunity, which could be associated with significant side effects. In this paper, the light will be shed on another innovative therapeutic strategy that rely on the biological modulation of the immune responses, together with the inhibition of the recruitment of the immune cells into the central nervous system after distortion of the blood brain barrier, as well as the enhancement of the regenerative ability towards the restoration of efficient blood brain barrier and the regenerative recovery of the neurological deficits. Key words: Multiple sclerosis, autoimmunity, regenerative therapy, mesenchymal stem cells and fibrinogen
Authors and Affiliations
Mohamed Shehata Ali Mohamed
Keywords
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- EP ID EP450700
- DOI 10.25002/tji.2018.774
- Views 83
- Downloads 0
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