Natural Excipients-An Alternative to Synthetic Excipients: A Comprehensive Review
Journal Title: International Journal of Pharmaceutical and Medicinal Reserach - Year 2014, Vol 2, Issue 4
Abstract
Though the utilization of natural excipients to deliver the bioactive agents has been hampered by the synthetic materials, but the added advantages offered by these natural excipients are their being non-toxic, less expensive and freely available. The performance of the excipients to some extent determines the quality of the medicines. The traditional concept of the excipients as any constituent other than the active substance has undergone a substantial evolution from an inert and cheap vehicle to an essential constituent of the formulation. Earlier used natural excipients are carrageenan, thaumatin, lard, shilajit, aerosil, myrobalan, storax. Excipients are any component other than the active substances deliberately added to formulation of a dosage form for it proper formulation. Novel drug delivery systems are developed to address the challenges of drug development such as bioavailability, permeability, and poor solubility. Global excipients markets are expected to grow rapidly with the emerging trends in the pharmaceutical industry. The pharmaceutical industry is marketing refinement in the physical structure of active pharmaceutical ingredients (APIs). The present review would facilitate to comprehend various natural excipients and their role in pharmaceutical products.
Authors and Affiliations
Abhishek Jain, Pinky Radiya, Raju Wadekar, Saleel Limaye, Chetan Pawar
Keywords
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