ROLE OF SERUM CHOLINESTERASE IN ACUTE ORGANOPHOSPHORUS POISONING: A HOSPITAL BASED CROSS SECTIONAL STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2015, Vol 4, Issue 30
Abstract
[b]BACKGROUND[/b]: Pesticide poisoning is a public health problem in developing countries. The anticholinesterase effect of OP compound is observed by decrease in serum pseudo cholinesterase level. The present study was designed to evaluate the relationship between the serum cholinesterase level and mortality following OP compound poisoning since it is not conclusive in previous studies. [b]MATERIAL AND METHODS[/b]: Estimation of serum cholinesterase was done in 82 patients admitted from Jan 2014 to Dec 2014. Patients were divided into 3 groups. Group I- S cholinesterase more 4500 IU/Lt, Group II- 2500-4500 IU/Lt, Group III- Less than 2500 IU/Lt. These 3 groups were compared with respect to age, sex, outcome, and amount of atropine used. [b]RESULTS[/b]:Total of 82 patients were studied. 51 patients in group I, 7 in group II and 24 in group III. An average day of hospital stay was more in group III patients. Total amount of Atropine required to treat group III patients was significantly higher than group I and group II patients. Mortality rate was significantly higher in group III patients (25%) as compared to group I patients (7.84%). [b]CONCLUSION[/b]: Estimation of serum cholinesterase is an useful tool to diagnose OP compound poisoning and predictor of severity of illness.
Authors and Affiliations
Giridhar Patil, Nimbal N. V, Arun Joshi , Archana Dambal , Madhavaranga M. P, Sunanda Halki
Keywords
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- EP ID EP148684
- DOI 10.14260/jemds/2015/745
- Views 106
- Downloads 0
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