A REVIEW ON BIOANALYTICAL TECHNIQUES
Journal Title: Int J of Preclin & Pharm Res - Year 2012, Vol 2, Issue 1
Abstract
ABSTRACT Quantitative determination of active pharmaceutical ingredient and its degradative products in biological fluids is a challenging task for an analyst due to difficulties and uniqueness of the sample. A systematic study of pharmaceutical products on human subjects whether patients or non-patient volunteers in order to discover or verify the clinical, pharmacological (including pharmacodynamics/ pharmacokinetics), adverse effects, with the object of determining their safety or efficacy and correcting plasma level with therapeutic action. Keywords: Bioanalytical method, Recent Analytical Techniques, LC-MS/MS.
Authors and Affiliations
*M. Sekar Babu
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF MULTICOMPONENTS IN BULK AND TABLET DOSAGE FORM
ABSTRACT A simple, accurate, precise, and sensitive and a highly selective UV-spectrophotometric method were developed for the simultaneous estimation of atorvastatin calcium and pyridoxine hydrochloride at a ma...
METHOD DEVELOPMENT AND VALIDATION OF RP-HPLC ANALYSIS OF BROMFENAC IN RABBIT PLASMA
ABSTRACT A simple, precise, rapid, and accurate reverse phase high performance liquid chromatography method was developed for the estimation of Bromfenac in Rabbit plasma by using Paracetamol as IS. The protein p...
DEVELOPMENT OF A STABILITY INDICATING RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF TRIMETHOPRIM, SULFAMETHOXAZOLE AND METYHL PARABEN IN ORAL SUSPENSION
ABSTRACT A gradient Simultaneous estimation by RP-HPLC Method were developed and validated for the quantification of Trimethoprim, Sulfamethoxazole and methyl paraben at single wavelength (275nm) in order to asse...
SUPER CRITICAL FLUID CHROMATOGRAPHY: AN OVERVIEW
ABSTRACT Supercritical Fluid Chromatography (SFC) is a form of normal phase chromatography, first used in 1962.SFC typically utilizes carbon dioxide as the mobile phase; therefore the entire chromatographic flow...
UV-SPECTROPHOTOMETRIC AND RP-HPLC METHODS FOR THE ESTIMATION OF TROXERUTIN IN BULK AND TABLET FORMULATION
ABSTRACT Troxerutin is used as an anti-coagulant drug for the treatment of Hemiplegia, Aphasia, Cardiac stem arteriosclerosis, etc. The aim of the present study is to develop a new analytical method for the estim...