APPLICATION OF RESPONSE SURFACE METHODOLOGY FOR THE MAXIMUM PRODUCTION OF TANNASE USING ASPERGILLUS FOETIDUS (MTCC 3557)

Abstract

 ABSTRACT Production of tannase by Aspergillus foetidus (MTCC 3557) using redgram husk as substrate was studied in submerged fermentation. The optimization of process parameters was carried out using Response Surface Methodology (RSM). RSM is applied for the Design Of Experiments (DOE) to evaluate the main effects, squared effects and interactive effects of the process parameters affecting the production of tannase in a submerged fermentation using Aspergillus foetidus (MTCC 3557) through a full factorial design. The optimum conditions were found to be a tannic acid concentration of 3.1 %, fermentation period of 97 h, temperature of 35.5°C and pH of 5.5 with a higher R2 value of 0.9251.The RSM revealed that a maximum tannase production of 157.6 U/ml was obtained at the optimum conditions. Keywords: Aspergillus foetidus, Response surface methodology, Submerged fermentation, Tannase.

Authors and Affiliations

Mohan S. K *1 , Viruthagiri T 2 and Arunkumar C

Keywords

Related Articles

 NOVEL SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL STUDIES OF SCHIFF BASE COMPLEXES OF 4-PYRIDINE CARBOXALDEHYDE

 ABSTRACT In the present study an intermolecular reductive Schiff base formation from 4-nitro pyridine and 4 pyridine carboxaldehyde carried out in the presence of iron powder and dilute acid. The Schiff base and...

ENHANCEMENT SOLUBILITY AND DISSOLUTION OF MEFENAMIC ACID BY MODIFIED STARCH

 The objective of the present research work is to enhance the dissolution profile of the mefenamic acid by Modified Starch as a carrier. Starch citrate was prepared by reacting the citric acid with starch at elevate...

 STUDIES ON SCREENING AND HISTOCHEMICAL LOCALISATION OF PHYTOCHEMICALS IN THE MEDICINAL PLANT BARLERIA LUPULINA LINDL

 ABSTRACT The genus Barleria lupulina Lindl of the family Acanthaceae belongs to the sub tribe Barlerieae of the tribe Justicieae sensu Benth & Hook. The present investigation mainly emphasized on the histoche...

 A RENEWABLE BIO-DIESEL FROM MICRO-ALGAE (A FUTURE’S NEED)

 ABSTRACT Biodiesels (fatty acid methyl esters) derived from oleaginous microbes (microalgae, yeast, and bacteria) are being actively pursued as potential renewable substitutes for petroleum diesel. Continued use...

 PROTECTION AGAINST ENDOTHELIAL DYSFUNCTION BY PIOGLITAZONE AND IRBESARTAN IN FRUCTOSE-FED DIABETIC RATS

 ABSTRACT The protective effects of metformin, pioglitazone, irbesartan, ramipril; and their combinations against oxidative stress and endothelial dysfunction in the aortic tissues in type-2 diabetic rats were inv...

Download PDF file
  • EP ID EP143863
  • DOI -
  • Views 96
  • Downloads 0

How To Cite

Mohan S. K *1, Viruthagiri T 2 and Arunkumar C (2014).  APPLICATION OF RESPONSE SURFACE METHODOLOGY FOR THE MAXIMUM PRODUCTION OF TANNASE USING ASPERGILLUS FOETIDUS (MTCC 3557). International Journal of Pharmaceutical Development & Technology, 4(3), 151-156. https://europub.co.uk/articles/-A-143863