METFORMIN LOWERS C-REACTIVE PROTEIN LEVELS AND IMPROVES THE MODIFIED BRIEF PAIN INVENTORY SCORES IN A WOMAN WITH ENDOMETRIOSIS – ASSOCIATED CHRONIC PELVIC PAIN: A CASE REPORT AND LITERATURE REVIEW
Journal Title: International Journal of Pharmaceutical Development & Technology - Year 2014, Vol 4, Issue 2
Abstract
Endometriosis is associated with low health-related quality of life and its incidence in the world is not decreasing, at least, in the developed economies. The aim of this case-report is to bring to the fore the beneficial effects of the insulin sensitizer, metformin, in endometriosis-associated chronic pelvic pain. Metformin lowered C-reactive protein levels and attenuated pain symptoms in a 48-year old woman diagnosed with endometriosis refractory to NSAIDs and hormone pills. The effect of metformin in endometriosis-associated chronic pelvic pain may be due to its anti-inflammatory and anti-oestrogenic effects and it warrants being further explored since endometriosis has no specific remedy at present.
Authors and Affiliations
Oriaifo SE , Oriaifo NI
Keywords
Related Articles
- EP ID EP121629
- DOI -
- Views 74
- Downloads 0
NANOPARTICLES AS SPECIFIED CARRIERS IN TARGETED BRAIN DRUG DELIVERY SYSTEM
The blood brain barrier represents an insurmountable obstacle for a large number of drugs including antibiotics, anti neoplastics and a variety of CNS active drugs especially neuropeptides. One of the possibiliti...
A REVIEW ON CLINICAL MANAGEMENT OF MULTIPLE SCLEROSIS
Multiple sclerosis affects the ability of nerve cells in the brain and spinal cord to communicate with each other. Nerve cells communicate by sending electrical signals called action potentials down long fibers cal...
EVALUATION OF IN VITRO ANTIOXIDANT AND GC/MS SPECTROSCOPIC ANALYSIS OF MEMECYLON UMBELLATUM BURM F FOR ITS BIOACTIVE COMPOUNDS
ABSTRACT Medicinal plants plays a major role in the discovery of new therapeutic agents for drug development. In recent times there is more attention towards them, due to the presence of bioactive compounds and t...
FORMULATION AND EVALUATION OF MEFENAMIC ACID EXTENDED RELEASE LIQUISOLID TABLETS
Liquisolid system refers to formulations formed by conversion of liquid drugs, drug suspension or drug solution in non-volatile solvents in to non-adherent, free flowing and compressible powder mixtures by blendin...
AN REVIEW ON (SMEDDS) SELF MICRO-EMULSIFYING DRUG DELIVERY SYSTEM
ABSTRACT In pharmaceutical solubility is one of the biggest problem to formulate the suitable dosage form because according to new chemical (drug) entities around 40% drug exhibit poor aqueous solubility and low...