COEXISTENCE OF CUTANEOUS MUCORMYCOSIS AND SCROFULODERMA IN AN IMMUNODEFICIENT CHILD
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 8
Abstract
Severe Combined Immunodeficiency (SCID) is a genetic disorder characterised by the disturbed development of functional T cells and B cells caused by numerous genetic mutations. (1) These patients are extremely vulnerable to infectious diseases and early death. (1) A 1-year-old child, known case of SCID since 8 months of age, presented with septic shock. He had a swelling on the left hand for 1 month and over left hand, which was a prior site of IV cannulation and swelling over axilla since 6 months. The child received multiple blood transfusions, though no bone marrow transplant was done. We entertained a differential diagnosis of cutaneous tuberculosis, atypical mycobacterial infection, deep fungal infection and foreign body granuloma for the left hand nodule. We thought of scrofuloderma with lymphadenopathy as a diagnosis for the axillary lesion. Biopsy of the hand lesion-multiple broad aseptate hyphae with granulomatous infiltrates suggesting mucormycosis. FNAC of axillary lymph node-necrotising lymphadenitis with AFB positive. Chest X-ray HRCT-PCP Pneumonia. He was started on IV Amphotericin-B.
Authors and Affiliations
Mahalakshmi , Gayathri , Maharaja , Adikrishnan , Sudha
Keywords
Related Articles
- EP ID EP154336
- DOI 10.14260/jemds/2016/84
- Views 96
- Downloads 0
COMPARISON BETWEEN TWO METHODS OF CIRCUMCISION- CONVENTIONAL (DORSAL SLIT AND EXCISION) VS. GUILLOTINE
BACKGROUND Circumcision is the surgical removal of the prepuce (foreskin), either in whole or in part. Religion, cultural, medical and recently public health reasons are known to be the major indications of the procedure...
PREVALENCE OF CHRONIC SUP
BACKGROUND Otitis media is an inflammation of the middle ear cleft. It is known to be one of the most common childhood infections. Children from developing countries having unfavourable environment witness an extraordina...
STUDY OF SERUM TOTAL THIOL LEVELS AND LIPID PEROXIDATION AS INDICATOR OF OXIDATIVE STRESS IN PATIENTS OF ACUTE CENTRAL SEROUS RETINOPATHY
BACKGROUND ''Central Serous Retinopathy (CSCR) is an idiopathic, commonly encountered retinal disease, in which stress has been implicated to play a possible role. Our study aimed to determine the role of oxidative stres...
RETINOBLASTOMA AND ITS CLINICOPATHOLOGICAL CORRELATION AT A TERTIARY CARE CENTRE
BACKGROUND Retinoblastoma is the commonest childhood primary malignant intraocular neoplasm that is often characterised by spontaneous regression. They display photoreceptor differentiation. This study provides the clini...
CLINICAL PROFILE OF SICKLE CELL ANAEMIA IN ADOLESCENT AND ADULT PATIENTS IN CENTRAL INDIA
BACKGROUND Sickle cell anaemia is a commonly encountered inherited haematological disorder in Central India. Despite the unicity of the genetic mutation that is responsible, clinical presentation of the sickle cell haemo...