Symptomatic Urinary Tract Infections Among Children Between Ages 1-5 Years In A Children’s Specialist Hospital, Ilorin, Kwara State, Nigeria
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2013, Vol 3, Issue 9
Abstract
This study investigated the incidence of symptomatic bacteriuria among male and female children aged between 1-5 years at chidren’s specialist hospital,Ilorin Metropolis, Ilorin, Kwara State. The aim of this study was to isolate the organisms responsible for symptomatic bacteriuria and determine the antibiotic susceptibility pattern of the isolates. The bacterial agents were isolated from a total of 200 early morning mid-stream urine samples collected between November 2005 and January 2006. Eight bacterial species were isolated out of which Escherichia coli was the most predominant with a frequency of 21.57% while Pseudomonas aeruginosa and Proteus mirabilis had the lowest frequency of 2.27% each. Their susceptibility patterns to seven antibiotics: Augumentin, Sparfloxacin, Erythromycin, Gentamicin, Chloramphenicol, Ceftazindine and Tetracycline was determined. Incidence of symptomatic bacteriuria among the children was found to be 44% with female preponderance over male. Female had a higher incidence of symptomatic bacteriuria(60.2%). Children aged 1 year had the highest incidence (26.1%) while those aged 2 years had the lowest (13.6%). The bacterial isolates showed varying degree of antibiotic resistance sensitivity pattern (between 50 and 80%) with Staphylococcus aureus and Staphylococcus epidermidis showing resistance to four antibiotics. All the isolates showed varying degrees of multidrug resistance with S.aureus, S.epidermidis and P.aeruginosa showing complete drug resistance. It is important to undertake regular monitoring of uroparhogens and their antibiotic susceptibility patterns and to find sufficient ways to control the abuse of antibiotics in the community
Authors and Affiliations
Oluwagunke Theresa Osamudiame
Keywords
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