Neutrophils and Neovascularization
Journal Title: Journal of Regenerative Medicine & Biology Research - Year 2023, Vol 4, Issue 3
Abstract
Neovascularization (NV) via growth of collateral arteries (arteriogenesis) and capillaries, arterioles and venules (angiogenesis) becomes impaired as ischemia from vascular disease progresses [1-3]. Our hypothesis is that overcoming hemodynamic and cellular obstacles to NV would yield an effective and durable option to surgical or catheter revascularization. A novel approach has been tested clinically that seeks to restore innate NV by overcoming obstacles that arise due to the multilevel arterial occlusive disease and progenitor cell deficits characteristic of Chronic Limb‐Threatening Ischemia (CLTI) [4-7].
Authors and Affiliations
Darwin Eton
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