P-Selectin is a Key Molecule Underlying the Pathophysiology of AspirinExacerbated Respiratory Disease
Journal Title: Immunological Disorders and Immunotherapy - Year 2016, Vol 1, Issue 1
Abstract
Recently, the evidence for platelet association with allergic diseases has been established by many researches. Activated platelets contribute to airway hyper reactivity, bronchoconstriction, airway inflammation and airway remodeling in asthmatic patients. We aimed to clarify platelet activation and key molecules on platelets, which are mainly associated with the mechanism underlying aspirin-exacerbated respiratory disease.
Authors and Affiliations
Chihiro Mitsui, Keiichi Kajiwara, Hiroaki Hayashi, Jun Ito, Haruhisa Mita, Emiko Ono, Noritaka Higashi, Yuma Fukutomi, Kiyoshi Sekiya, Takahiro Tsuburai, Kazuo Akiyama, Kazuhiko Yamamoto and Masami Taniguchi
Keywords
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