Peculiaritis of serum content of СD8 differentiating antigens soluble forms and their connection with disorders of lungs ventilation in the case of chronic obstructive lungs disease
Journal Title: Медицинский альманах - Year 2016, Vol 2, Issue 2
Abstract
Objective: to study the relationship between serum content of soluble (s-) forms of the СD8 molecules and obstructive disorders of pulmonary ventilation in patients with chronic obstructive pulmonary disease (COPD). The study involved 50 patients with COPD. All the patients underwent physical examination, spirometry. The serum levels of sCD8 antigens were investigated using ELISA method; results were compared with serum samples of 30 healthy donors. It has been shown that low level of sCD8 molecules is a risk factor for severe COPD. An analytical model of the relationship between FEV1 and sCD8 can be used in clinical practice for the purposes of the screening assessment of the immune status of the patients.
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- EP ID EP215401
- DOI 10.21145/2499-9954-2016-2-35-38
- Views 75
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