PHARMACOGNOSTIC AND PHYTOCHEMICAL EVALUATIONS OF THE LEAVES OF HOLOPTELIA INTEGRIFOLIA ROXB
Journal Title: Pharma Science Monitor-An International Journal Pharmaceutical Sciences - Year 2010, Vol 1, Issue 2
Abstract
Holoptelea integrifolia belongs to the family of Urticaceae. The bark and leaves are bitter, astringent, anthelmintic, diabetes, helminthiasis, skin disease, intestinal disorder, leprosy, rheumatism. Evaluation of the fresh, powdered and anatomical sections of the Holoptelia integrifolia leaves were carried out to determine the macromorphological, micromorphological, numerical and phytochemical profiles. Macroscopic studies indicated presence of the leaf of having 7.5-8.2 cms and 4.5-5.0 cms in size, apex is acute, oval in shape, entire margin, cordate base, reticulate pinnate types of venation, petiole is long, surface is glabrous, upper epidermis dark green in color, lower epidermis lighter in color with characteristic odour and bitter taste. In the microscopic studies, the leaves showed the presence of trichomes, collenchyma, vascular bundles, spongy parenchyma, palisade cells and stomata. Phytochemical evaluation revealed the presence of alkaloids, flavonoids, tannins, saponins, terpenoids, glycosides and absence of steroids and anthraquinones. The investigations also included leaf surface data quantitative leaf microscopy and fluoroscence analysis. The results of the study could be useful in setting some diagnostic indices for the identification and preparation of a monograph of the plant.
Authors and Affiliations
Dharmeshkumar Prajapati* , Natvarlal M. Patel
IN VITRO ANTIBACTERIAL ACTIVITY OF CLEOME VISCOSA LINN
The present investigation is aimed to carryout in vitro antibacterial activities of the methanol and aqueous extracts of Cleome viscosa against seven bacterial species. To evaluate antibacterial activity, the agar well...
IN VITRO DISSOLUTION ENHANCEMENT OF ALBENDAZOLE BY PREPARATION OF INCLUSION COMPLEXS WITH HP- ß CYCLODEXTRIN
With the introduction of combinatorial chemistry and high throughput screening, the properties of new chemical entities shifted towards higher molecular weight and increasing lipophilicity that results in decreasing aq...
A SYSTEMATIC REVIEW ON NATURAL MEDICINE USED FOR THERAPY OF DIABETES MELLITUS OF SOME INDIAN MEDICINAL PLANTS
Diabetes mellitus is one of the world’s major diseases. It currently affects an estimated 143 million people worldwide and the number is growing rapidly. In the India, about 1- 5% population suffer from diabetes or rel...
SELF MICRO EMULSIFYING DRUG DELIVERY SYSTEM
Oral route has always been preferred route for formulators and has dominated over other routes of administrations. However this preferred route is limited to those drugs molecule that are permeable across the gastric m...
PHARMACOEPIDEMIOLOGY AND PHARMACOTHERAPHY OF ARTHRITIS IN NORTH GUJARAT
Several incidence and prevalence studies of RA have been reported during the last decades, suggesting a considerable variation of the disease occurrence among different populations. This epidemiology study has been don...