Pharmacological Approaches and Management of Brain Stroke
Journal Title: International Journal of Research in Pharmacology & Pharmacotherapeutics (IJRPP) - Year 2014, Vol 3, Issue 4
Abstract
Stroke is a common health problem in present days which is identified by the symptoms including face drooping, speech difficulty, sudden numbness, and sudden trouble in vision, loss of balance or coordination, severe headache. The epidemiological studies have shown about 750,000 people have stroke per year in which 80% have ischemic stroke and remaining 20% have hemorrhagic stroke but there are very few treatments available in present that can treat stroke and their deformities. The rate of morbidity and mortality is higher in stroke and it is 4th leading cause in US and 3rd one in developing countries. Hence a good pharmacological management is required for the better treatment and recovery from stroke. The pharmacological management includes use of thrombolytics, antiplatelet therapy, hypolipedaemics, antihypertensive, antioxidants, clot disruption technique, rehabilitation technique and their combinations such as clopidogrel + aspirin, Aspirin + dipyridamole, telmisartan + ramipril, melatonin + tpa, IgG–glial cell line-derived neurotrophic factor (GDNF) and IgG– tumor necrosis factor receptor (TNFR). Therefore, a variety of combinational studies are required for the more beneficial outcomes in the future.
Authors and Affiliations
Parihar Lalit
Keywords
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