PHOSPHATE TYPE KIDNEY STONE (BRUSHITE) FORMATION IN GEL: A MORPHOLOGICAL STUDY ON GROWTH PATTERNS
Journal Title: Journal of Pharmaceutical and Scientific Innovation - Year 2017, Vol 6, Issue 3
Abstract
Brushites are most commonly found phosphate stones in the kidneys, ureters and urinary bladder. The study was conducted to observe the possible growth patterns of brushite crystals in gel for 14 days. The crystals formation was observed as a bullet, needle, platy, columnar shaped and their aggregates. These shapes were further explained by Magono and Lee meteorological classification. Beside the morphology, average size, number and weight of crystals were also observed at 7th and 14th day. Energy Dispersive X-ray, Fourier Transform Infra Red spectroscopy and Scanning Electron Microscopy were used to characterize the crystals. These results can help to determine the promotion, modulation and inhibition of the crystals which will be helpful to evaluate the risk factors and prophylactic management of brushite type urinary stones.
Authors and Affiliations
Salman Ahmed, Muhammad Mohtasheemul Hasan, Zafar Alam Mahmood
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