PRE-CLINICAL INVESTIGATION OF ANTI-TUSSIVE ACTIVITY OF HIBISCUS ROSA-SINENSIS ON GUINEA PIG
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 9
Abstract
Ayurveda suggests that decoction of leaves of Hibiscus rosa-sinensis could be beneficial to reduce cough. Codeine and other synthetic antitussive agents shows number of side-effects and thus to find better and safer alternate Hibiscus rosa-sinensis was evaluated for its antitussive activity.Dried powder of flower part of Hibiscus rosa-sinensis was extracted with methanol and the practical yield of methanolicextract was found to be 1% W/W.Anti-tussive effect of methanolic extract of Hibiscus rosa-sinensis was studied in Histamine chamber using citric acid (7.5%W/V) induced cough model, in which the methanolic extract of Hibiscus rosa-sinensis significantly decreased the number of coughing. From this we concluded that methanolic extract of Hibiscus rosa-sinensis possess antitussive activity.
Authors and Affiliations
Karna Jani , Parth Gandhi , Tejas Ganatra , Tusharbindu Desai , Pravin Tirgar
Keywords
Related Articles
- EP ID EP135315
- DOI -
- Views 100
- Downloads 0
EFFECTS OF AQUEOUS EXTRACT OF EUGENIA OPERCULATA ROXB. ON NORMAL AND STREPTOZOTOCIN INDUCED DIABETIC MICE
The aim of this study is to determine the antihyperglycemic properties of an aqueous extract of Eugenia operculata leaves on blood glucose and body weight of normal and Stz induced diabetic albino mice and also to determ...
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF CARBIDOPA, LEVODOPA AND ENTACAPONE IN ITS BULK AND TABLET DOSAGE FORM BY UPLC
The study was conducted with the purpose to method develop and validate a Ultra Performance Liquid Chromatography method UV detector to determine Levodopa, Carbidopa and Entacapone content in table preparation using MeOH...
PROTECTIVE EFFICACY OF HUMBOLDTIA BRUNONIS WALL ON DOXORUBICIN INDUCED OXIDATIVE DAMAGE
Liver, heart and kidney are the frequent targets of the toxicants as liver involved in metabolism, heart supplies O2 to entire body and kidney involves in the excretion and re-absorption of the substances. The principle...
CUMIN (CUMINUM CYMINUM L.; UMBELLIFERAE) CULTIVATION IN WEST BENGAL PLAINS, KALYANI, NADIA
Cumin (Cuminum cyminum L.; Family: Umbelliferae) is a seed spice of commercial importance as well as it is a potential medicinal herb with immense therapeutic uses not withstanding its significance in health food formula...
INDUCED MUTAGENESIS IN ABELMOSCHUS MOSCHATUS (L.) MEDIK
Dry seeds (cultivar I – tall, branched, moisture content 3.5%; cultivar II – dwarf, unbranched, moisture content 1.5%) of Abelmoschus moschatus (L.) Medik (Family: Malvaceae; Common name: Ambrette; English name: Musk mal...