Pre-emptive analgesic effects of paracetamol infusion versus intramuscular ketorolac in patients undergoing elective laparoscopic cholecystectomy: A comparative study
Journal Title: Medpulse International Journal of Anesthesiology - Year 2019, Vol 10, Issue 1
Abstract
Background: Minimally invasive surgery has displayed advantages over open surgery but still causes mild to moderate post-operative pain. Preemptive analgesia is one of the strategies of pain management which has beneficial effects on the occurrence and intensity of postoperative pain. Method: A total of 120 patients, aged 19-59 years with ASA grades of I/II were scheduled for elective laparoscopic cholecystectomy under general anaesthesia. They were randomized into two equal groups of 60 patients each. Group A received intravenous Paracetamol infusion (1gm) and group B received intramuscular Ketorolac (30 mg) 15 minutes before surgery. The two groups were compared statistically in terms of demography, intraoperative hemodynamics, postoperative pain (VAS), and need for rescue analgesic with tramadol. Results: Demographic profile and hemodynamic parameters were comparable in both the groups. The Mean VAS scores on the intergroup comparison post-operatively at 30 minutes, 1 hour, 3 hours and 6 hours were found to be lower for intramuscular ketorolac group and was statistically significant (p-value<0.05). Rescue analgesic when required was seen within 3-6 hours post-operatively and was used much earlier in paracetamol group. Conclusion: Pre-emptive intramuscular ketorolac (30 mg) is more effective in reducing postoperative pain scores (VAS) after laparoscopic cholecystectomy in the first 6 hours as compared to 1 gm intravenous paracetamol infusion.
Authors and Affiliations
Sifna Tahir, Majid Mushtaque, Umar Qadir Bacha
Keywords
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- EP ID EP589636
- DOI 10.26611/10151014
- Views 225
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