Prevalence of weak D antigen and Rh positive and Rh negative blood groups among blood donors - A Six year experience in a blood bank of tertiary health care centre of central India
Journal Title: Medpulse International Journal of Pathology - Year 2018, Vol 6, Issue 1
Abstract
Background: After ABO group system, Rh D is clinically one of the most important blood group systems. Testing of all Rh negative units (by routine method) is must to detect weak D antigen by IAT method. When test show agglutination with anti D and D (u) it is labelled as Rh (D) positive. If test show no agglutination it is labelled as Rh (D) negative. Objectives: To know the Prevalence of weak D antigen (Du) and Rh positive and Rh negative blood groups in blood donors of blood bank of tertiary health care centre of Bhopal (M.P). Material and Method: Retrospective study among donors blood samples of Rh negative by immediate spin tube method were tested for weak D by indirect antiglobulin test (IAT) by tube method. Observation and Results: Among 11607 healthy blood donors, 11131(95.89%) were RhD factor positive while, 476(4.09%) were RhD negative. Out of 476 RhD factor negative donors 05(0.04%) were weak D positive. The study conducted on donors of Blood Bank of Peoples College of Medical Science and Research Centre Bhanpur Bhopal (M.P) from January 2012 to December 2017. Conclusion: According to many studies weak D antigen is immunogenic and is capable of producing alloimmunisation if transfused to RhD negative subjects so weak D detection prevent alloimmunisation in Rh negative patients.
Authors and Affiliations
Reetesh Kumar Gujar, Upasana Uniya, Deepika Kirar
Keywords
Related Articles
- EP ID EP460897
- DOI 10.26611/105615
- Views 67
- Downloads 0
Study of endometrial hyperplasia using morphometry assisted techniques in a tertiary care hospital
Background: Endometrial hyperplasiais an important cause of abnormal uterine bleeding. The diagnosis of endometrial hyperplasia continues to be a diagnostic dilemma for pathologists due to histopathological variations. T...
A histopathological study of spectrum of gastrointestinal tract lesions: Two year study
Background: Gastrointestinal tract (GIT) is an important site for wide variety of lesions which include congenital, inflammatory and neoplastic conditions. H. Pylori has been implicated in varied range of gastric lesions...
C-reactive protein in cerebrospinal fluid: An evaluative and correlative study
Objectives: This study aimed to test Cerebro Spinal Fluid and importance of C Reactive. Protein in Meningitis cases. CSF analysis is done on suspected meningitis patients and biochemical values of CSF was studied and com...
Seroprevalence and trends of anti- Hepatitis C antibodies among voluntary blood donors in a tertiary care hospital blood bank in South India
Background: The transfusion of blood and its components is life saving but each transfusion has its own risks of adverse effects including the transmission of Transfusion Transmissible Infections (TTI). The aim of this s...
A clinicopathological study of 48 cases of lupus nephritis
Background: Systemic lupus erythematosus is a multi-systemic disorder which commonly affects the kidneys and remains the most dangerous life threatening complication.1Renal manifestationsare highly variable and patients...