Primary Gall Bladder Carcinoma: A one-year prospective study at a tertiary care center.
Journal Title: Journal of Medical Sciences - Year 2018, Vol 21, Issue 2
Abstract
Background: Gallbladder carcinoma is not an uncommon clinical entity in the Indian scenario, unlike western countries. It is predominantly a disease of females. Association between gallstones and Gallbladder carcinoma is strong. Its carcinogenesis follows a progression through a metaplasia−dysplasia−carcinoma sequence. An early diagnosis is essential as this malignancy progresses silently with a late diagnosis, often proving fatal. Therefore, every gallbladder should be subjected to routine histopathological examination because with the identification of an early gallbladder carcinoma a curative resection may be possible, and these patients have a good survival rate. Methods: This was a prospective study done on 22 cases of gallbladder carcinomas over a period of 1 year from 1st November 2017 to 1st November 2018. Results: Present study showed that gallbladder cancer is predominantly a disease of elderly females. In the present study, abdominal pain 18 cases (81.81%) followed by anorexia 15 cases (68.18%)and dyspepsia14cases(63.63%) was the most common presenting symptom present. Cholelithiasis was found in only 5 (22.72%) of our patients. Adenocarcinoma was the most common histopathologic variant found in 20 cases (90.90%) followed by squamous cell carcinoma 2cases (9.09%). Conclusions: Every gallbladder should be subjected to routine histopathological examination because with the early-stage disease a curative resection may be possible, and these patients have good long-term survival.
Authors and Affiliations
Zubaida Rasool, Nuzhat Samoon, Nazia Bhat, Huzaifa Nazier, Kanika Gupta
Keywords
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