Prolonged febril syndrome of rheumatological origin. Report of three cases.
Journal Title: Revista Cuarzo - Year 2018, Vol 24, Issue 1
Abstract
The present work describes three cases with Prolonged Febrile Syndrome (PFS) with definitive diagnosis of rheumatological disease. The first, a 29-year-old man with febrile peaks of 40 ° C, myalgias and cervical adenopathies; trip 30 days ago to tropical region, which led to think about an infectious etiology; however, after persistence of fever despite antimicrobial coverage, paraclinical studies are extended with ferritin finding at 2208 μg / l suggestive of Still's Disease from the adult to the tenth day of stay. The second is a 19-year-old man, with symptoms of abdominal pain asso-ciated with a temperature of 40 ° C with no relevant history; Abdominal ultrasound evidences he-patomegaly and pleural effusion; during the stay, presented tonic-clonic seizures and pancytopenia with hemolytic anemia, after ruling out infectious disease and malignancy, an immunological profi-le with positive ANAS and Lupus Anticoagulant was requested and a diagnosis was made towards Systemic Lupus Erythematosus on the eleventh day of hospitalization, with improvement after immunomodulatory management. Finally, a female patient of 14 years with a history of arthralgias, cervical and submaxillary adenopathies, morbilliform exanthema and fluctuating fevers (38-39.9 ° C) of a month of evolution that persisted despite negative polycultures and broad spectrum antibio-tic therapy. which are extended laboratory studies finding ferritin of 3156 μg / l on the ninth day of stay and is diagnosed with Still's disease of the child. The prevalence of rheumatological diseases in the PFS, has been increasing allowing the precise approach to other etiologies previously not considered among its causes
Authors and Affiliations
Cadavid González, V. , Guzmán, R. , Mejía Guatibonza, M. , & Barrera, M.
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