Qualitative Phytochemical Analysis and in Vitro Fungal Activities of Citrus aurantifolia L. and Carica papaya L. Leaves Extracts on Pathogenic Fungi
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 3
Abstract
The use of medicinal plants, which have fewer side effects and economically cheaper, have been taken into consideration recently. Citrus aurantifolia and Carica papaya leaves are not only known for their nutritional benefits but also considered to possess medicinal properties. The main aim of the study was to determine the antifungal activities of Citrus aurantifolia and Carica papaya leaves on some pathogenic fungi (Aspergillus, Candida and Penicillium) isolated from female genital tract. Leaves of Citrus aurantifolia and Carica papaya were collected from Onu-Ebonyi in Ebonyi State. Three different concentrations (300 mg/ml, 150 mg/ml and 75 mg/ml ) of leaves ethanol extract were prepared and introduced into bored holes of organisms cultured on potato dextrose agar(PDA). The result showed that leaf extract of lime had higher zones of inhibition diameter on three fungi species compare to leaf ethanol extract of Carica papaya. There were increase on zones of inhibition of both leaves extract as the concentration increases from 75 mg/ml to 300 mg/ml. Phytochemical screening indicated the presence of flavonoids, alkanoids, tannins, saponin and protein in Carica papaya but alkanoids and tannins in Citrus aurantifolia. The result showed that Citrus aurantifolia and Carica papaya possess antifungal activities but Citrus aurantifolia showed more inhibitions on Aspergillus, Candida and Penicillium than Carica papaya.
Authors and Affiliations
Dimphna N. Ezikanyi, Catherine V. Nnamani, Joy N. I hejirika3
Keywords
Related Articles
- EP ID EP384580
- DOI 10.9790/3008-1103036872
- Views 81
- Downloads 0
Sero-Activity of Chikungunya Virus at the Kenyan Coast after the 2004 Epidemic
Chikungunya virus (CHIKV) is an alphavirus of Semliki Forest virus antigenic complex. Seroprevalence of CHIKVwas measured after the reported 2004CHIKV epidemic in Coastal Kenya and factors associated with seropositivity...
Validation of Russell’s Viper Venom Detoxification Activity of Azadirachta indica through In Silico Method
Azadirachta indica A. Juss. (neem) is one of the Indian medicinal plants used as antidote to snake venom particularly against viper envenomation. In the present study 335 phytochemicals reported from Azadirachta indica w...
Stability Indicating Rp-Hplc Method For The Simultaneous Estimation Of Atazanavir And Cobicistat In Bulk And Tablet Dosage Form
The combination of Atazanavir and Cobicistat combined dosage form is used for the treatment of HIV-1 infection. Review of Literature reveals that there is no stability indicating HPLC methods for simultaneous estimation...
In Vitro and In Vivo Hepatoprotective Activity of Madhuca Longifolia L Leaves on Carbon Tetrachloride Induced Rats
Administration of Madhuca longifolia Methanolic Extract (MLME) and derivative of Madhucic Acid (dMA) a bioactive from it leaves and standard drug silymarin in rats showed significant hepatoprotective action against CCl4...
The impact of left ventricular thickness in hypertensive heart disease on right ventricular function: An Echocardiographic Strain Study
Background:In spite of heart remodeling such as left ventricular hypertrophy affects both left and right ventricles due to ventricular interdependence; still a few studies had examined the outcomes of these effects on ri...