Real-World Outcomes of Anti-VEGF Treatment for Neovascular Age-Related Macular Degeneration in Turkey: A Multicenter Retrospective Study, Bosphorus Retina Study Group Report No: 1
Journal Title: TÜRK OFTALMOLOJİ DERGİSİ - Year 2018, Vol 48, Issue 5
Abstract
Objectives: To evaluate the real-world outcomes of intravitreal anti-vascular endothelial growth factor (anti-VEGF) treatment in neovascular age-related macular degeneration (nAMD) patients. Materials and Methods: Multicenter, retrospective, interventional, non-comparative study. The records of nAMD patients treated with an anti-VEGF agent on a pro re nata treatment regimen basis between January 2013 and December 2015 were reviewed. The patients who completed a follow-up period of 12 months were included. Primary outcome measures of this study were the visit and injection numbers during the first year. Results: Eight hundred eighty eyes of 783 patients met the inclusion criteria for the study. Mean number of visits at month 12 was 6.9±2.5 (range: 1-15). Mean number of injections at month 12 was 4.1±1.9 (range: 1-11). Mean visual acuity at baseline and months 3, 6, and 12 was 0.90±0.63 LogMAR (range: 0.0-3.0), 0.79±0.57 LogMAR (range: 0.0-3.0), 0.76±0.57 LogMAR (range: 0.0-3.0), and 0.79±0.59 LogMAR (range: 0.0-3.0), respectively. Mean central retinal thickness at baseline and months 6 and 12 was 395±153 μm (range: 91-1582), 330±115 μm (range: 99-975), and 332±114 μm (range: 106-1191), respectively. Conclusion: The numbers of visits and injections were much lower than ideal and were insufficient with the pro re nata treatment regimen.
Authors and Affiliations
Abdullah Özkaya, Levent Karabaş, Cengiz Alagöz, Zeynep Alkın, Özgür Artunay, Selim Bölükbaşı, Gökhan Demir, Mehmet Demir, Ali Demircan, Burak Erden, Gürkan Erdoğan, Erdem Eriş, Havva Kaldırım, İsmail Umut Onur, Özen Osmanbaşoğlu, Sezin Özdoğan Erkul, Mine Öztürk, İrfan Perente, Kübra Sarıcı, Nihat Sayın, Dilek Yaşa, İhsan Yılmaz
Keywords
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- EP ID EP407507
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