Relation between uric acid and chronic kidney disease
Journal Title: Medpulse International Journal of Biochemistry - Year 2018, Vol 7, Issue 2
Abstract
Aims: To study the relationship of serum uric acid with chronic kidney disease and assess the relationship of increased serum uric acid as an established risk factor for chronic kidney disease. Materials and Methods: A hospital based study was conducted on 30 subjects with CKD were selected as cases and 30 subjects with normal kidney function tests were selected as controls for the present study. Results: Serum uric acid significantly increased (p<0.001) in cases compared to controls. Pearson’s correlation analysis showed a significant positive correlation between serum uric acid and serum creatinine(p<0.001) and negative correlation with eGFR(p<0.001). Conclusion: serum uric acid is significantly higher and strongly associated with chronic kidney disease.
Authors and Affiliations
Shakuntala Masti
Electrolyte abnormalities in chronic heart failure patients on treatment with two different drug regimens
Background: Heart failure is a complex clinical syndrome, impairing the ability of the cardiac ventricles to fill with or eject blood. Drug therapy for Chronic Heart Failure (CHF) is aimed at providing symptomatic relief...
Leptin, Insulin resistance and Dyslipidemia in Acanthosis Nigricans
Background: Leptin is a adipocytokine hormone, with 167 amino acids. It acts via hypothalamic neuronal pathway, signalling satiety centre and controlling body weight. Acanthosis nigricans is associated with Leptin, obesi...
Study of serum Malondialdehyde, nitric oxide and vitamin E in rheumatoid arthritis patients before and after the supplementation of vitamin E
Background: Rheumatoid arthritis (RA) is a chronic systemic inflammatory disorder that may affect many tissues and organs – skin, blood vessels, heart, lungs and muscles but principally attacks the joints, producing a no...
Protein bound hexose and protein bound hexosamine as diagnostic indicators in severe depression
Background: Depressive illness is considered to be a psychoneuro-immunological disorder due to peripheral immune activation through the release of pro inflammatory cytokines. Cytokines enhance the hepatic synthesis of gl...
Blood lactate levels and its association with survival outcome in polytrauma patients
Background: Lactate as a marker for tissue hypoperfusion is an established biomarker for morbidity and mortality in patients with sepsis and trauma, but has limited clinical application. Aim of this study is was signific...