Report concerning the colaborative study for establish of reference standard eficacity of Rifamycin
Journal Title: Medicamentul Veterinar / Veterinary Drug - Year 2015, Vol 9, Issue 2
Abstract
The Microbiology Laboratory from the Institute for the Control of Veterinary Biological Products and Medicines participated in a collaborative study in order to determine the potency of rifamycin CRS, batch 4, according to the protocol sent by the EDQM (European Directorate for the Quality of Medicines) coordinating of the study. The purpose of the study was to establish the potency of the batch 4 rifamycin in the characterization of the substance as reference standard. Potency was determined by microbiological method, based on comparison of the inhibition zones of growth of micro-organisms sensitive to those of a reference standard, as specified in European Pharmacopoeia, Chapter 2.7.2. - Microbiological testing of antibiotics. After analysis of received data from participants and their statistical processing by the EDQM, the potency of the batch 4, rifamycin - reference materials, was established in 870 UI/mg.
Authors and Affiliations
Simona Sturzu, Daniela Tirsinoaga, Ioana Tihulca, Mariana Dumitrache, Alina Draghici, Valentina Nastase
Keywords
Related Articles
- EP ID EP90310
- DOI -
- Views 142
- Downloads 0
Theoretical elements of veterinary therapeutics
The present essay describes, logically and in a synthetic way, the main elements of veterinary therapeutics. The first part refers to the concept of dose and the main factors affecting its establishment, presenting the e...
Short guide of cardio-vascular medication in animals
The medication of heart and blood in animals rise many problems in the current veterinary practice, on the one hand because of lack or very few of functional investigation means and of absence of specific training in thi...
Validarea metodei de determinare a furazolidonei şi oxitetraciclinei în prezența substanţelor înrudite prin cromatografie de lichid de înalta performanţă
Obiectivul acestui studiu a fost dezvoltarea unei metode simple, precise, rapide şi exacte de determinare a furazolidonei, oxitetraciclinei şi substanţelor înrudite din produsele farmaceutice veterinare. Produsul farmace...
Eficacitatea pastei antihelmintice FENBENDAZOL 30% în ciatostominoza cabalinelor
Ciatostominoza cabalinelor este o helmintoză a intestinului gros produsă de paraziți din familia Strongylidae, subfamilia Cyathostominae. Ciatostominele (strongili nemigratori) reprezintă o provocare atât pentru paraz...
The thyroid and the thyroid hormones
The thyroid gland is located in the cervical fascia were it is divided in two lateral lobes, right and left, disposed on both sides of the trachea, and unlike other vertebrates, the cat does not have an isthmus that conn...