Research progress of platelet lysates in the field of regenerative medicine and cell therapy
Journal Title: Chinese Journal of Blood Transfusion - Year 2023, Vol 36, Issue 7
Abstract
Human platelet lysates(HPL), as a new type of biomaterial, can promote tissue repair, cell proliferation and inflammation control. This paper introduced the development of HPL in the field of regenerative medicine and cell therapy and summarizes their application. The potential of HPL to promote cell proliferation was used as an entry point to show its advantages as a supplement of cell culture medium. Since there is currently no standard procedure for HPL preparation, this paper sorts out the standardization elements such as raw materials source, donor variability and preparation technology, in order to provide reference for the establishment of standards of relevant industry in the future.
Authors and Affiliations
Jiahui ZUO, Yiming LI, Shuwei YANG, Liqin HUANG
Keywords
Related Articles
- EP ID EP738600
- DOI 10.13303/j.cjbt.issn.1004-549x.2023.07.021
- Views 36
- Downloads 0
Validation of the detection method for residual human coagulation factor Ⅺ in human prothrombin complex
Objective To establish an enzyme-linked immunosorbent assay (ELISA) method for the determination of residual human coagulation factor Ⅺ in human prothrombin complex and validate the method. Methods Human factor Ⅺ was rea...
Serological characteristics and molecular mechanisms of occult hepatitis B virus infection in blood donors
[Objective] Abstract: Objective To analyze the serological characteristics of occult hepatitis B virus infection (OBI) in blood donors, and to explore the molecular mechanism of HBV S gene mutation in the immune escape o...
Study on the distribution of ABO blood group in patients with pancreatic cancer
Objective To investigate whether there is a correlation between the differences in ABO blood group distribution in patients with pancreatic cancer, and to evaluate the relative risk. Methods Patients with pathological di...
Study on the change of neutralizing antibody level in plasma donors after a third shot of inactivated novel coronavirus vaccine
Objective To investigate the trend of neutralizing antibody level in plasma donors who received the 3rd shot of inactivated novel coronavirus vaccine. Methods Three commercial ELISA kits for novel coronavirus neutralizat...
Desalination effect on FⅧ components: a compartive study among 5 desalination methods
Objective To compare the desalination effects of five desalination methods and their effects on the components for human coagulation factor Ⅷ(FⅧ), and provide reference for selection of protein desalination methods. Meth...