Research progress on the influence of ligands on the stability of albumin
Journal Title: Chinese Journal of Blood Transfusion - Year 2024, Vol 37, Issue 1
Abstract
It is necessary to improve the stability of human serum albumin in response to the complex temperature, light and other conditions during the manufacture and storage. In this paper, the stabilization effect and simple stabilization mechanism of ligands on albumin were described from the perspective of ligand binding to albumin.Through review and comparison, it can be concluded that the common ligand sodium octanoate mainly plays a role in improving thermal stability, and the common ligand N-acetyl-L-tryptophan mainly plays a role in improving antioxidant activity, N-acetyl-L-methionine has better antioxidant and anti-photooxidation than N-acetyl-L-tryptophan.
Authors and Affiliations
Lieqing YANG, Rongchao YIN, Lei YANG, Jinrong JING, Haitao FANG, Jiaquan CHEN, Weixin LIU
Keywords
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- EP ID EP738754
- DOI 10.13303/j.cjbt.issn.1004-549x.2024.01.021
- Views 49
- Downloads 0
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