Retrospective comparison of pneumonia occurence in patients with chronic obstructive pulmonary disease using inhaled combination or inhaled long acting beta agonist alone
Journal Title: Ege Tıp Dergisi - Year 2015, Vol 54, Issue 1
Abstract
Aim: Data from recent studies revealed that the use of combinations of inhaled corticosteroids and long acting beta 2 agonists (LABA) may increase pneumonia risk in chronic obstructive pulmonary disease (COPD) patients. The aim of this retrospective study is to compare the occurence of pneumonia in COPD patients who received regularly inhaled corticosteroid and LABA combinations with the patients who received inhaled LABA only. Materials and Methods: Sixty-two COPD patients were included in the study. Patients were divided into 2 groups according to the inhaled agents they used; “combination group” (31 patients; 26 male, 5 female; median age±SD: 68±9) and “LABA group” (31 patients; 27 male, 4 female; median age±SD: 66±8). Medical recotds of patients were retrospectively evaluated and all patients were contacted via telephone Results: Ten patients in combination group had severe or very severe COPD (FEV1 <50%) versus 8 patients in LABA group. Seventeen episodes (54%) of pneumonia was detected in the combination group, whereas 10 (32%) in LABA group (p=0.06). Diabetes mellitus was present as a comorbidity in two patients in the combination group and in three in the LABA group. Conclusion: Since study population was limited, statistical difference between the two groups was found to be insignificant. But, there was a trend of higher incidence of pneumonia in the combination group, similar to previous studies.
Authors and Affiliations
Tuğba ÖNALAN, Ayşegül BAYSAK, Jülide Çeldir EMRE, Özer ÖZDEMİR, Mustafa Hikmet ÖZHAN
Keywords
Related Articles
- EP ID EP342193
- DOI -
- Views 81
- Downloads 0
Keratocystic odontogenic tumor: A retrospective study of 64 cases
Aim: The purpose of this retrospective study was to evaluate the clinicopathological features of 64 patients with keratocystic odontogenic tumor (KCOT). Materials and Methods: The patients ranged in age at the time of di...
Maple syrup urine disease with cranial imaging findings
Maple syrup urine disease (MSUD) also known as branched-chain ketoaciduria, is caused by a deficiency of branched-chain alpha-ketoacid dehydrogenase complex. It has autosomal recessive inheritance. It is characterized by...
Bel ağrılı hastalarda ağrı, kinezyofobi ve yaşam kalitesi arasındaki ilişki
Amaç: Bel ağrısı klinikte en sık karşılaşılan ve yaşam kalitesini olumsuz etkileyen muskuloskeletal bir problemdir. Kinezyofobi varlığı bel ağrısı tedavisini olumsuz yöne etkileyebilir ve kişinin özür oranını arttırabili...
Guillain Barré syndrome variant with facial diplegia and paresthesias: A case report and review of the literature
Guillain Barré syndrome (GBS) is a disorder characterized by areflexia and progressive ascending lower extremity weakness. Bilateral peripheral facial diplegia and paresthesia is a rare GBS variant in which the preceding...
İzole hiperbilirubinemi ile başvuran akut apandisit olgusu
Akut apandisit hastalarında, sarılık ve yaygın karın ağrısı nadir görülen bulgulardır. Çoğunlukla geç dönemde başvuran komplike ve perfore/gangrenöz apandisit ile ilişkilendirilir. Sarılığa neden olan hiperbilirübinemini...