RP-HPLC method development and validation for simultaneous estimation of Lopinavir and Ritonavir in tablet dosage form
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2017, Vol 5, Issue 1
Abstract
Simultaneous Estimation of Lopinavir and Ritonavir were carried out by RPHPLC using Acetate buffer (PH 6.5): Acetonitrile (55:45) and column Phenomenex Luna C-18 (250*4.6 mm, 5um) as a stationary phase and peak was observed at 255 nm which was selected as a wavelength for quantitative estimation. After the development of the method, it was validated for specificity, linearity, precision, accuracy, robustness and ruggedness studies.
Authors and Affiliations
Masanam Jyothi Bindu, K. Narendra Kumar Reddy, G Himabindu
Keywords
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