Serosurvey of human T cell lymphotropic virus I/II among blood donors in Gombe (Nigeria)
Journal Title: International Journal of Blood Transfusion and Immunohematology - Year 2016, Vol 6, Issue 1
Abstract
Aim: This study was carried out to determine the prevalence of human T cell lymphotropic virus I/II (HTLV I/II) among blood donors at the Federal Teaching Hospital Gombe (FTHG), North-eastern, Nigeria. Methods: A total of 355 blood donors were recruited at the hematology department of FTHG for a hospital based cross-sectional study and were screened/confirmed for HTLV I/II by ELISA and western blot methods. Results: Seroprevalence of HTLV I/II among the 355 participants with mean age of 30.77 years (±8.27) was 6.5% on screening with ELISA but confirmed to be 0% by western blot. Majority were males, 352 (99.2%) and mostly (45.9%) between 21–30 years of age. Donors for family replacements predominated (85.1%) with more than half (58.6%) being first time blood donors. Conclusion: This study reveals the absence of HTLV I/II among blood donors in Gombe North-eastern Nigeria. It also highlights the possibility of false positivity in some of the reported prevalence of HTLV I and II from some parts of Nigeria that were based on screening tests only. The importance of confirmatory testing in all research works on HTLV (including HTLV 3 and HTLV 4) is further strengthened with this study. There is however the need for a larger study and the use of molecular diagnostics to reconfirm this assertion.
Authors and Affiliations
Mohammed M. Manga, Adeola Fowotade, Saleh Yuguda, Rasheed Ajani Bakare, Ibrahim Musa Yola, Ewean Chukwuma, Girei Ahmed Iya
Keywords
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- EP ID EP209942
- DOI 10.5348/ijbti-2016-24-OA-4
- Views 136
- Downloads 0
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