Serum lipid levels in diabetes mellitus patients with and without diabetic retinopathy: A prospective study
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH IN MEDICAL SCIENCES - Year 2017, Vol 3, Issue 8
Abstract
Diabetes Mellitus is a group of metabolic disorder characterized by chronic hyperglycaemia. Blinding diabetic eye disease is now one of the fourth major causes of blindness in the world. Diabetic retinopathy (DR) is a major microvascular complication of diabetes. A prospective study was conducted involving 200 patients of diabetic retinopathy. The patients were divided in two groups i.e. study and control group. The relation with age wise distribution to severity of diabetic retinopathy in patients was maximum in the age group of 51-60 years. We found positive correlation of serum lipids level with development and severity of diabetic retinopathy. Thus hypolipidemic drugs can be used in diabetic retinopathy with dyslipidemia to retard its progression. Longer duration of diabetes and poor glycemic control led to worsening of retinopathy. The need for a simple, inexpensive, repeatable, and fairly reliable screening test is the need for the present time for the timely detection of diabetic retinopathy and prevent visual loss. The present study demonstrated statistically significant difference of higher serum lipid levels in diabetic retinopathy patients than non diabetic retinopathy patients. Higher Total cholesterol, Triglyceride and LDL levels are associated with more severe retinopathy and increased duration is associated with increased prevalence and more severe diabetic retinopathy. This effective monitoring of lipid profile and glycemic control would be beneficial in these patients
Authors and Affiliations
Swati Prajapati, Rashmi Kujur, U. S. Tiwari, K. P. Ranjan*
Keywords
Related Articles
- EP ID EP569748
- DOI 10.22192/ijcrms.2017.03.08.013
- Views 114
- Downloads 0
The Effect of low Serum Vitamin D Levels on the Prevalence of Preeclampsia in Pregnant Women
As the most common metabolic disorder during pregnancy, diabetes causes chronic resistance to insulin through secreting extra volumes of insulin. Diabetes is a chronic disease which develops when pancreas does not produc...
Isolation and Antimicrobial sensitivity pattern of Klebsiella pneumoniae from sputum samples in a tertiary care hospital
Background: Gram negative pathogens are an important cause of community and hospital acquired infections throughout the world. Klebsiella pneumoniae has become one of the more common cause of these infections and one of...
The impact of preoperative breast MRI on the surgical management of newly diagnosed non metastatic breast cancers
Background: Preoperative MRI (magnetic resonance imaging) of the breast is likely to accurately stage the disease and thereby influence the surgical decision making in newly diagnosed non metastatic breast cancers. We as...
Evaluation of acetylcholinesterase inhibitory activity of Brahmi nei, a Siddha formulation using in - vitro techniques.
Acetylcholine is the chief organic chemical responsible for the function of brain and various other activities of human body. It plays a major role in neurotransmission and performs its function in both Central nervous s...
Detection of Intestinal Metaplasia among Sudanese Patients with Chronic Gastritis by Using Combined Alcian Blue- PAS Technique
Background and aim: Gastric cancer (GC) is one of cancer that leads to death in the world. GC is usually developed through a series of mucosal changes from non-atrophic gastritis to atrophic gastritis (AG), intestinal me...