The impact of preoperative breast MRI on the surgical management of newly diagnosed non metastatic breast cancers
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH IN MEDICAL SCIENCES - Year 2017, Vol 3, Issue 5
Abstract
Background: Preoperative MRI (magnetic resonance imaging) of the breast is likely to accurately stage the disease and thereby influence the surgical decision making in newly diagnosed non metastatic breast cancers. We assessed the impact of preoperative contrast-enhanced MRI in surgical management of women with early breast cancer. Design: Prospective retrospective study of 48 cases of newly detected non metastatic breast cancers in an Oncology unit of a tertiary care teaching hospital. Enrolled patients were assessed with preoperative MRI of breasts and findings were compared with standard sonomammography findings. Appropriate stage wise treatment plan was devised in conjunction with MRI findings and were corroborated with histopathological examination results. Outcomes: Primary outcome was assessment of changes in the surgical management of newly detected non metastatic breast cancer as a result of findings revealed in the preoperative MRI of breasts. The agreement of assessment between new MRI findings vis-à-vis histopathology of new lesion was also analyzed Conclusions: Addition of preoperative MRI to routine mammography did not have a statistically significant impact on surgical management of newly detected non metastatic breast cancers. No statistically significant difference was noted in the number of lesions detected by sonomammography and MRI.There was significant difference between histologically proven and unproven cases in patients where the treatment plan was changed, i.e. 37.5% (3/8) vs 62.5% (5/8) amongst 08 cases where treatment plan was changed following MRI. Changes in treatment plan accrued higher percentage of negative results on histopathological examination.
Authors and Affiliations
Col (Dr. ) Puneet Takkar* , Surg Lt Cdr (Dr. ) Hari JP** , Surg Lt Cdr (Dr. ) Khushdeep Kaur***
Autologous Platelet-Rich Plasma In Diabetic Foot Ulcers, New Preparation Technique
Aim of work: To assess the healing of diabetic foot ulcers attributed to newly technique preparation of platelet-rich plasma (PRP) compared with that in the control group with conventional procedures. Methods: A prospect...
Dupuytren Contracture
Dupuytren's disease is a common and disabling fibroproliferative condition of the hand. The condition is named after Baron Dupuytren, a French surgeon, who developed eminent surgeon Henry Cline's initial observations reg...
Study on the association between Hyperuricemia and Albuminuria in patients of type 2 Diabetes Mellitus
Introduction: Type 2 diabetes mellitus is associated with a high rate of complications related to cardiovascular disease and diabetic nephropathy, retinopathy, and neuropathy. Type 2diabetes patients with increased urina...
Diagnostic utility of Ki-67 as a proliferative marker & the expression of Galectin-3 in Neoplastic and Non-neoplastic lesions of thyroid.
Thyroid neoplasms constitute the most commonly occurring endocrine tumors worldwide. Owing to the wide spectrum of clinical behaviour & varied therapeutic responsiveness, early diagnosis of thyroid tumors and appropriate...
A Review on tuberculosis in Human Immunodeficiency Virus infection
TB is the most common opportunistic infection and the leading cause of death among people living with HIV and AIDS. Tuberculosis a disease caused by a microorganism called Mycobacterium tuberculosis. Pulmonary TB is an a...