Serum uric acid and urinary albumin in patients of type II diabetes mellitus
Journal Title: Medpulse International Journal of Biochemistry - Year 2017, Vol 4, Issue 2
Abstract
Diabetes mellitus has been known to be a state of oxidative stress with excess generation of free radicals contributed by several mechanisms including hyperglycemia. Uric Acid is the final oxidation product of purine metabolism in humans. Whether Uric Acid acts as an antioxidant or prooxidant is the matter of debate. Hyperuricemia is associated with an increased risk of complications. Increased levels could be injurious to the kidneys and predictive of progression of Renal disease. Objecives of study are to estimate Uric Acid levels in type II diabetics and study its correlation with urinary albumin excretion. Fasting venous samples along with urine were collected from patients visiting Govt Medical College, Aurangabad. Serum Uric Acid levels and urinary albumin were estimated. Uric Acid concentration was significantly higher in diabetics. Increased levels of uric acid were associated with increased urinary albumin excretion. The importance of uric acid as a risk factor for renal injury and increased urinary albumin excretion rate is worthy of further investigation.
Authors and Affiliations
Gulajkar Supriya Rameshrao, Bina M Gadhiya, A P Thorat
Keywords
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