Serum uric acid and urinary albumin in patients of type II diabetes mellitus
Journal Title: Medpulse International Journal of Biochemistry - Year 2017, Vol 4, Issue 2
Abstract
Diabetes mellitus has been known to be a state of oxidative stress with excess generation of free radicals contributed by several mechanisms including hyperglycemia. Uric Acid is the final oxidation product of purine metabolism in humans. Whether Uric Acid acts as an antioxidant or prooxidant is the matter of debate. Hyperuricemia is associated with an increased risk of complications. Increased levels could be injurious to the kidneys and predictive of progression of Renal disease. Objecives of study are to estimate Uric Acid levels in type II diabetics and study its correlation with urinary albumin excretion. Fasting venous samples along with urine were collected from patients visiting Govt Medical College, Aurangabad. Serum Uric Acid levels and urinary albumin were estimated. Uric Acid concentration was significantly higher in diabetics. Increased levels of uric acid were associated with increased urinary albumin excretion. The importance of uric acid as a risk factor for renal injury and increased urinary albumin excretion rate is worthy of further investigation.
Authors and Affiliations
Gulajkar Supriya Rameshrao, Bina M Gadhiya, A P Thorat
Keywords
Related Articles
- EP ID EP258974
- DOI -
- Views 188
- Downloads 0
Comparative study of electrolyte levels with various level of HbA1C in diabetes mellitus patients
Objective: The aim of this study is to estimate of electrolyte levels in patient with diabetes mellitus and compare the result among the various levels of HbA1C and also to find out the correlation between electrolytes a...
Prevalence of subclinical hypothyroid in rural population
Background: Subclinical Hypothyroidism is a common endocrinological problem worldwide. The present study is a cross sectional study to determine the prevalence of sub clinical hypothyroidism in adults in rural Telangana....
Bilirubin content and dielectrophoresis of erythrocytes of patients suffering from jaundice
The paper reports the dielectrophoretic behaviour of erythrocytes of blood of the patients suffering from jaundice. The erythrocytes suspended in isotonic solution were subjected to geometry. For this purpose, a pin diel...
Comparative assessment of oxidative stress and enzymatic antioxidants in primigravidae pregnant and non-pregnant women
Background: The generation of reactive oxygen species and the activation of antioxidant defence mechanisms are important components of female reproductive physiology. It's impairment alters cellular signalling and can da...
Biochemical parameters and its association with quality of life in patients with diabetic foot ulcers
Background: Diabetic foot ulcer (DFU) is a serious complication of Diabetes mellitus (DM) with significant impact on the quality of life(QoL). Various biochemical parameters can play important role in evaluating QoL in D...