Situs Invertus Totalis in a Patient with Bilateral Papillary Serous Cystadenocarcinoma Ovary: Rare Association with Review of Literature
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 3
Abstract
Situs Invertus Totalis (SIT) is a rare congenital anomaly inherited as autosomal recessive disorder. It is characterized by transposition of thoracic and abdominal visceras including dextrocardia. It occurs in 1:8,000 to 1:20,000 of general population. The patient usually remains asymptomatic with normal life expectancy, unless a gastrointestinal or a cardiac anomaly is present. 35 years female resident of Haryana state (India), presented with pain, lump abdomen and secondary amenorrhoea. USG revealed bilateral ovarian mass. On MRI, Situs Invertus Totalis was incidentally discovered with bilateral ovarian mass and ascites. USG guided FNAC was done for bilateral ovarian mass and, it was diagnosed as bilateral ovarian carcinoma (papillary type). Later Total Abdominal Hysterectomy with bilateral salpingo-oopherectomy was done. Diagnosis of papillary serous cystadenocarcinoma was confirmed by histomorphology and immunohistochemistry. Here, we report a case of bilateral papillary serous cystadenocarcinoma of ovary in an incidentally discovered case of Situs Invertus Totalis with review of literature. Although SIT is not considered a premalignant condition widely but possibility of malignant lesion and its correlation is yet to be ruled out. SIT cases requires a great care due to abnormal anatomy. Further studies on genetics and molecular biology are needed to explore and establish the relation.
Authors and Affiliations
Kalpana Mangal, Nehal Minda, Savita Saharan
Keywords
Related Articles
- EP ID EP547766
- DOI 10.21276/ijmrp.2017.3.3.001
- Views 75
- Downloads 0
Efficacy of CPAP in Treatment of Hyaline Membrane Disease in NICU
Hyaline membrane disease also called as respiratory is a common cause of admission in the NICU. It is a common health problem in preterm babies due to deficiency of surfactant. Surfactant reduces surface tension in the a...
Exposure to Violence among Physicians Working at the Primary Care in the Kingdom of Bahrain
Background: Violence against healthcare workers is a critical problem, regardless of its form. It has a range of physical and psychological outcomes, affecting their health and productivity. Published studies about the p...
Microbiological Profile Among Patients With Fungal Infections: A Hospital Based Study
Background: There are various fungal infections of humans. Among them candidiasis, mucormycosis, etc are common. The present study was conducted to assess various fungal infections in study population. Materials & Method...
Hyponatremia in Children with Acute Lower Respiratory Tract Infections: An Institutional Based Study
Background: Lower respiratory tract infection (LRTI) is among the serious health problems specifically in less than 5 years of age needing hospitalisation and attributes to 30 % of deaths yearly worldwide especially due...
Meckel Gruber Syndrome: A Rare Entity
Meckel-Gruber Syndrome (MKS) was first described by J R Meckel in 1822. It is an autosomal recessive disorder, and is caused by the failure of mesodermal induction. The typical triad of Meckel-Gruber Syndrome (MKS) invol...