Skin and soft tissue infections: Clinico-microbiological and drug resistance profile
Journal Title: Medpulse International Journal of Microbiology - Year 2019, Vol 10, Issue 2
Abstract
Background: Early diagnosis, appropriate antibiotic therapy and timely surgical intervention are the need of the hour in managing skin and soft tissue infection. Improperly managed skin and soft tissue infections pose a great challenge and add on to morbidity and mortality in the patients. Objectives: This study aims to study the clinical infections, type of Skin and soft tissue infections and risk factors. It also aims at determining the bacteriological profile and the antibiogram of the isolates obtained. Materials and methods: The study was conducted in a teaching hospital with a total of 34 SSTI cases during August 2018 to September 2018 .Samples were inoculated in blood agar, and MacConkey agar and further biochemical tests were performed according to the standard protocol. Antibiotic Susceptibility testing was done for the isolates as per the CLSI guidelines. Results: Among the 34 cases, 55 bacterial isolates were obtained. Of the 34 cases, 11 (32.35%) had cellulitis, 3 (8.82%) had abscess, 14(41.17%) had necrotizing fascitis, 4 (11.76%) had carbuncle and 2(5.88%) had diabetic foot ulcers. The commonest bacteria isolated was Acinetobacter spp (n=11), E. coli (n=10), Pseudomonas spp (n=8), Methicillin sensitive Staphylococcus aureus (n=8), and Methicillin resistant Staphylococcus aureus (n=6). Conclusions: In this study, Acinetobacter spp, E. coli followed by MSSA was the most common organism isolated. With the varied pathogens and their antimicrobial susceptibility patterns, it is essential to start definitive treatment after microbiological culture and sensitivity results are obtained.
Authors and Affiliations
Annet Olinda Dsouza, Rajeswarie S
Keywords
Related Articles
- EP ID EP590568
- DOI 10.26611/10081022
- Views 95
- Downloads 0
Drug resistance profile of Klebsiella Species from clinical isolates in a tertiary care hospital
Background: Klebsiella species are widely distributed in nature occurring as commensals in intestines and saprophytes in soil and water. These are associated with wide variety of opportunistic and nosocomial infections,...
Comparative study of enzyme linked immunosorbent assay and immunochromatography for rotavirus detection in children below five years with acute diarrhoea
Background: Early diagnosis of rotavirus infection prevents unnecessary use of antibiotics, minimizes it’s spread and helps to determine the appropriate treatment. Rapid test using latex agglutination or lateral flow imm...
A trend of antibiotic resistance pattern of klebsiella pneumoniae isolated from various clinical samples in patients attending tertiary care hospital Saurashtra region, Gujarat, India
Background: Klebsiella pneumoniae has been associated with different types of infections and one of the most important aspects of Klebsiella pneumoniae is emergence of multi-drug resistant strains. Moreover, extensive us...
Speciation and resistotyping of coagulase negative staphylococci from clinical samples in a tertiary care hospital
Background: Coagulase negative Staphylococci (CONS) are the indigenous flora of the human skin and mucous membrane. They have long been considered as non-pathogenic and were rarely reported to cause severe infections. Ho...
Seroprevalence of HIV infection in thalassemia patients in a tertiary care hospital
Background: The general incidence of thalassemia trait in India varies between 3 and 17%. Children with thalassemia are susceptible to HIV because they receive multiple blood transfusions. Prevalence of HIV infection in...