Sociodemographic features of organophosphate poisonings and the relationship between time of pralidoxime administration and mortality
Journal Title: Dicle Tıp Dergisi - Year 2013, Vol 40, Issue 4
Abstract
Objective: Organophosphates are commonly used in agriculture and mostly lead to intoxication. In this study, we examined the sociodemographic features, clinical findings, and the relationship between time to treatment with pralidoxime and mortality in patients with organophosphate poisoning treated in our clinic. Methods: We retrospectively examined hospital records of 179 patients who were managed for organophosphate poisoning in our clinic, between January 2001 and November 2009. Sociodemographic data, clinical findings, laboratory results, complications during follow-up, and outcomes were recorded. The patients were grouped as died and survived, and comparison of sociodemographic and clinical features, laboratory results, and treatment outcomes were performed. Results: Among 179 patients, 133 (74.3%) were female, 46 (25.6%) were male and mean age was 27.1+11.7 years. Fifteen (8.3%) patients died. Illiteracy rate among those who died was 66.6%, while it was 30.4% in those who survived. Among those who died, 13 (86.6%) had nicotinic and 14 (93.3%) had CNS signs. Assessment of cases by the time to PAM administration revealed mortality rates of 4.47% (n=6), 19.4 % (n=7), and 22.2% (n=2) for the first 3 hours (n= 134), 3-6 hours (n=36), and after 6 hours (n=9), respectively. Conclusion: A great majority of patients presenting with organophosphate poisoning were of low educational status, which was linked with mortality, indicates the importance of education. In addition, mortality rate was lower in patients who were administered PAM at an earlier period in the treatment process, suggesting the role of early PAM administration in reducing mortality. Key words: Organophosphate, pralidoxime, mortality
Authors and Affiliations
Mehmet Güllü, Ali Kadiroğlu, Murat Orak
Keywords
Related Articles
- EP ID EP162196
- DOI 10.5798/diclemedj.0921.2013.04.0331
- Views 108
- Downloads 0
A rare condition observed in pregnancy: gastric carcinoma; Case report
Gastric cancer is quite rare during pregnancy. Gastrointestinal symptoms consequent to pregnancy such as nausea, vomiting, and abdominal pain make the diagnosis of the disease difficult. At diagnosis, patients present...
A Case of Neonatal Sepsis due to Listeria monocytogenes Serotype 4b: Case report and literature review
Listeria monocytogenes has been often leads to infection in pregnant women, newborns and patients with impaired immune response. Serotypes 1/2a, 1/2b and 4b are responsible on majority of human infections and outbreaks...
The level of hopelessness in the students of an occupational education center and affecting factors
The aim of this survey was to define the hopelessness levels in the students of an occupational education center and the definition of the factors affecting them. Materials and methods: The survey is a descriptive type...
Ailevi Akdeniz Ateşi ve Crohn hastalığı birlikteliği
Ailevi Akdeniz Ateşi otozomal resesif geçiş gösteren, kısa, akut, kendini sınırlayan ateş ve poliserozit atakları ile karakterize bir hastalıktır. Akdeniz çevresindeki ülkelerde daha sık görülmektedir. İnflamatuar bar...
Metotreksat ve dilatasyon-küretaj ile tedavi edilen sezeryan skar gebeliği: Olgu sunumu
Sezeryan skar gebelikleri ektopik gebeliklerin ciddi komplikasyonlara sebep olabilen en nadir formudur. 37 yaşında, geçmişinde 4 gebelik 4, 2 doğum 2ve bir sezaryen bulunan kadın hasta 6 hafta 2 gündür adet görememe v...