SPECTRUM OF MAGNETIC RESONANCE IMAGING ABNORMALITIES OF HYPOXIC ISCHEMIC ENCEPHALOPATHY IN PRETERM AND FULL-TERM PATIENTS AT TERTIARY CARE HOSPITAL IN INDIA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 51
Abstract
BACKGROUND Hypoxic Ischemic Encephalopathy (HIE) is one of the most common neurological abnormalities causing neonatal mortality and severe neurological deficits in children. HIE also constitutes an important diagnostic dilemma in both full term and prematurely born infants. Many times HIE goes unnoticed in early stages, only to present in later stages of life as a severe neurological deficit in children. The various patterns seen in HIE depend on the duration and severity of hypoxia, and brain maturation level. Therefore, imaging findings of HIE highly depend upon the timing of imaging. MRI plays a vital role in early detection of the various spectrum of HIE. It not only helps radiologist to the right path of diagnosis but also guides paediatrician in determining the prognosis of the development of the infant. Aims and Objectives- To retrospectively study the spectrum and various patterns in which HIE affects preterm and full-term infants and to evaluate the common presentations on MRI. MATERIALS AND METHODS This Retrospective descriptive study was done on 50 patients, diagnosed with HIE, visiting the Department of Radio-diagnosis, GMC, Amritsar for MRI examination on 1.5 Tesla Siemens machine. Various patterns by which HIE affects preterm and full-term infants were studied. RESULTS Our study included 50 patients diagnosed with HIE. 18 (36%) of these patients were pre-terms and 32 (64%) patients were full term. 35 (70%) of these were males and 15 (30%) were females. The most common clinical presentation was developmental delay. Most common MRI finding in preterm patients was periventricular leukomalacia and in full term patients was T2 and FLAIR periventricular and subcortical white matter hyperintensities. CONCLUSION MRI has become the primary imaging modality in patients suffering from HIE and plays a pivotal role in identification, localization and characterization of the underlying pattern of disease in affected patients. The combination of various sequences in MRI help in early diagnosis of HIE lesions and are highly needed early management of the disease.
Authors and Affiliations
Daisy Gupta, Deepak Rana
Keywords
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- EP ID EP550478
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