Spinal epidural with bupivacaine 0.5% alone and bupivacaine 0.5% with fentanyl 1mcg/kg in prolonging the duration of intra-operative analgesia

Journal Title: Medpulse International Journal of Anesthesiology - Year 2017, Vol 8, Issue 1

Abstract

Objectives: To compare the study and efficacy of bupivacaine versus bupivacaine with fentanyl in prolonging the duration of intraoperative analgesia. Study Design: Randomized controlled double blinded study. Materials and Methodology: A fifty American society of anaesthesiologists of category I and II undergoing for elective lower limb surgery under combined spinal epidural anaesthesia were studied in this prospective randomized double blinded study. First group I(n=25) was given inj.bupivacaine 0.5% intrathecally with epidural topup of 0.5% bupivacaine was given and Group II (n=25) was given inj. Bupivacaine 0.5% intrathecally with epidural top up of bupivacaine 0.5% with fentanyl 1mcg/kg. Vitals , duration of analgesia ,duration of blockade and complications were analyzed both intraoperatively and postoperatively. Results: The mean two segment regression time was found to be 147.00 in group l patients and 150.80 in group II. The two segment regression time in both the groups were comparable. The mean duration of intra operative analgesia was found to be 200.20 mins in group I and 293.20 in group ll patients. The 'P' value was <0.001 which was statistically significant. The group l patients had 56.60 mins more post-operative analgesia compared to group ll. In the group ll,17 patients got highest sensory block of T6 compared to 3 patients in group I. In the group ll, 5 patients got highest sensory block of T7 compared to 7 patients in group I .In the group ll,3 patients got highest sensory block of T8 compared to 12 patients in group I. AND 'P’ value is below 0.01 which is statistically significant. Group ll patients the 'P' > 0.005 statistically insignificant. Conclusion: Its is concluded that subarachnoid block with 0.5% bupivacaine and 1mcg fentanyl is a more safer and better option for patient undergoing elective lower limb surgeries.

Authors and Affiliations

M Dakshinamoorthy, D Harishprabhakaran

Keywords

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  • EP ID EP440571
  • DOI 10.26611/10158110
  • Views 164
  • Downloads 0

How To Cite

M Dakshinamoorthy, D Harishprabhakaran (2017). Spinal epidural with bupivacaine 0.5% alone and bupivacaine 0.5% with fentanyl 1mcg/kg in prolonging the duration of intra-operative analgesia. Medpulse International Journal of Anesthesiology, 8(1), 49-53. https://europub.co.uk/articles/-A-440571