Starch Coated Silver Nanoparticles Using Hygrophila Auriculata L for Controlled Released of Ofloxacin
Journal Title: Journal of Advance Nanobiotechnology - Year 2017, Vol 1, Issue 1
Abstract
In this study, we developed encapsulating Ofloxacin (OFL) drug loaded starch coated Hygrophila auriculata L mediated silver nanoparticles (H-AgNPs) [Ofloxacin loaded starch coated-H-AgNPs]. HAgNPs were characterized by UV-Visible spectrophotometer, XRD, TEM. The OFL-loaded starch coated-H-AgNPs was evaluated by particle size, surface charge, entrapment efficacy, and effect of pH in drug release proļ¬le. Additionally, drug entrapment efficacy (EE) was up to 43%; OFL -starch-H-AgNPs showed a pH-responsive drug release in vitro. The OFL release was nearly 79% at pH 4.5 and 68% at pH 7.4.The current work proves the potential of pharmacology that involves a fusion of advanced techniques from nanoscience to develop the biology and used in the fields of drug delivery.
Authors and Affiliations
Diptikanta Acharya
Keywords
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- EP ID EP290398
- DOI 10.28921/jan.2017.01.02
- Views 129
- Downloads 0
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