Studies on antioxidant and anthelmintic activity of two Streptomyces species isolated from Western Ghat soils of Agumbe, Karnataka
Journal Title: Journal of Pharmacy Research - Year 2010, Vol 3, Issue 1
Abstract
The Western Ghats are well known for their rich and unique assemblage of flora and fauna. The present study was conducted to determine antioxidant and anthelmintic potential of two actinomycetes isolates recovered from Western Ghats soils of Agumbe, Karnataka. The isolates were identified as Streptomycetes based on colony appearance, spore arrangement, biochemical and staining characteristics.The antioxidant activity of butanol extract of the culture broth of Streptomyces sp. No 1 and 2 was assessed using DPPH free radical assay and Fe+3 reducing assay. The solvent extracts of the isolates showed a dose dependent antioxidant activity. Anthelmintic activity was determined in adult Indian earthworm model. A marked dose dependent paralysis and death of worms was observed revealing anthelmintic activitiy. Among isolates, Streptomyces sp. No. 2 was found to possess marked antioxidant and anthelmintic efficacy than Streptomyces sp. No. 1. The observed activities of the isolates might be due to active principles present in the solvent extracts. Isolation and purification of the compounds possessing these potentials in the butanol extracts are to be carried.
Authors and Affiliations
T. R. Prashith Kekuda 1*, K. S. Shobha 2, R. Onkarappa 2
Keywords
Related Articles
- EP ID EP84681
- DOI -
- Views 139
- Downloads 0
In vitro evaluation of free radical scavenging activity of medicinal plant Polyalthia longifolia (Sonner.) Thw. leaf extract
The present study was aimed at investigating the antioxidant activities of the ethanol and chloroform extracts of the leaves of Polyalthia longifolia (Sonner.) Thw. (Annonaceae). The antioxidant activities of the extrac...
Thevetia peruviana (Pers.) Schum . : A plant with enormous therapeutic potential
An extensive review on the growing requirements, its botany and the medicinal value of this plant has been incorporated. This plant has been known for its diverse range of therapeutic importance in ethno medicine, Ayurv...
FT-IR study of the effect of aluminium on the muscle tissue of Cirrhinus mrigala
In fish tissues, muscle is the major contributor of proteins and the whole mass of the body. The aim of this study is to evaluate the changes in the biochemical compositions in the muscle of Cirrhinus mrigala fingerling...
Flavonoid Extraction from Passiflora alata Dryander (Passifloraceae) - Using Factorial Design
This paper investigated the influence of different flavonoids extraction found in the powder of the aerial parts of Passiflora alata Dryander, using the factorial design as a statistical tool, enabling to assess and opt...
Effect of oilfield wastewater on microbiota of a fresh water in Nigeria
Effect of oilfield wastewater to the Microbiota of the fresh river water was investigated. This was conducted by the determination of some physicochemical parameters which included pH, turbidity, total dissolved solids (...