Studies on serum soluble endoglin: An indicator for preeclampsia
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2018, Vol 5, Issue 4
Abstract
Introduction To study the concentration of serum soluble endoglin during second trimester pregnancy and monitor for the development of preeclampsiaMaterials and Methods Seventyfive healthy singleton pregnant women in second trimester was evaluated in this study ELISA technique was used for measuring the concentration of Serum soluble endoglin Patients with increased level of serum endoglin were monitored for signs and symptoms of preeclampsiaResult Thirty five pregnant women developed preeclampsia among 75 pregnant women The mean value for sENG in cases was 87 14 and control 59 06 The normal value of serum sENG varies from 254 to 706 ngml Hence it is higher than the normal limit in casesConclusions The concentration of sENG was studied and women were monitored for development of preeclampsia The present study showed that women with increased serum soluble endoglin levels developed preeclampsia later Hence it is suggested that soluble endoglin will be useful in predicting pre eclampsiaKeywords Endoglin Preeclampsia ELISA sENG
Authors and Affiliations
Archana A, Brindha G, Ursula Sampson
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