Study of CD4 Count Level in HIV-TB Co-Infection in ART Patients Before And After Anti-Tubercular Treatment
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 1
Abstract
Introduction: HIV and TB co-infection is when people have both HIV infection and also active TB disease. HIV infected individuals have a high risk of developing active TB following infection and also have increased mortality. Worldwide TB is one of the leading cause of death among people living with HIV. Initiation of ART during the course of ATT has been shown to reduce mortality in co-infected persons, especially in those who are severely immunosuppressed. Absolute CD4 cell levels are the main markers of disease severity in patient with HIV, as well as the best markers yet for disease progression. Aims and Objective: The study was aimed to determine the effect of HIV-TB co-infection on CD4 count level. Materials and Methods: A study was carried out at the ART of RIMS, Ranchi from July 2016 to June 2017. A total of 61 HIV-TB co-infection patients, who attended ART clinic receiving ART and ATT treatment during the study period. Results: In the study, more patients of HIV-TB co-infection had lower CD4 count. Of total 61 patients, 36 were less than 200 CD4 count, 11 were between200-350, 7 were between 350-500 and 7 were more than 500. Conclusion: CD4 lymphocyte cells are the primary targets of HIV. It is used to stage the patient’s disease, determine the risk of opportunistic illnesses, assess prognosis and response to therapy.
Authors and Affiliations
Ashok Kumar Sharma, Ashwini Verma, Manoj Kumar, Manish Kumar Sinha, Amber Prashad, Kumari Seema
Keywords
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- EP ID EP531325
- DOI 10.21276/ijmrp.2018.4.1.134
- Views 83
- Downloads 0
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