Study of effect of rational hyperoxia in perioperative period on rate of surgical site infection
Journal Title: Medpulse International Journal of Surgery - Year 2019, Vol 9, Issue 1
Abstract
Background: Oxygen supplemented at a concentration higher than 40–50 % for at least 2 h perioperatively is expected to reduce surgical site infections (SSI). Supplemental perioperative oxygen has been variously reported to halve or double the risk of surgical wound infection. Objectives: To study the effect of rational hyperoxia in perioperative period on rate of surgical site infection. Material and Methods: It was a prospective randomized control trial, with total sampel of 537. Sample was divided into clean wound of class 1 and contaminated wound of class 2. Further subdivided into hyperoxic (study) and normoxic (control) groups. Results: Out of a total of 537 patients, 335 patients were male and 202 patients were females. Male to female ratio was 1.67:1. Excision of swelling (79) was most common surgery among class 1 and primary suturing (85) was seen as most common surgery in class 2. 33.71% of patients in control group and15.75% patients in study group had SSI. Over al risk difference, attributable risk% and relative risk was 0.178, 53.13% and 2.13 respectively. Most common organism isolated from the SSI wounds in this study was pseudomonas followed by Acinetobacter suggesting hospital acquired cross infections and hence a need for more stringent asepsis protocols. No adverse event pertaining to hyperoxia such as nausea, vomiting and pulmonary complication were observed during the study. Conclusions: Overall rate of SSI for clean and clean contaminated surgeries of present study is comparable with rate of SSIs in other Indian studies, but is more than the rate of SSI for clean and clean-contaminated surgeries in other developing countries.
Authors and Affiliations
Mihir K Shah, Divyang Chavda
Keywords
Related Articles
- EP ID EP471560
- DOI 10.26611/106916
- Views 153
- Downloads 0
Management outcome of thoracic injuries - A study of 180 cases
Background: Thoracic injuries are widely ranging from simple contusion of chest wall or simple rib fracture to fatal rupture of heart from crushing injuries Advanced Trauma life support (ATLS) protocol forms the bedrock...
A comprehensive evaluation of fistula in ano in Maharashtra population
Fistula in Ano is a non-malignant treatable lesion of the rectum and the anal canal. Cryptoglandular infection accounts for approx. 90% of these cases. Majority of the infections are acute and few cases contributed by ch...
Effect of alcohol ban on road traffic accidents in national highways near Belgavi
Background: Road traffic accidents are one of the major cause of death in developing countries like INDIA. Most of the road traffic accidents occur under the influence of alcohol. Most of the victims are teen aged boys....
Assessment of clinical and biochemical features among malignant and benign cases of surgical jaundice
Background: Jaundice is a generic term for the yellow pigmentation of skin, mucous membranes, sclera that is caused by a heterogenous group of disorders. During the last decade, our evolving ability has been to image the...
Comparative study on post operative complication between mini laparotomy cholecystectomy and standard conventional open cholecystectomy
Background: Surgical procedures like open cholecystectomy (OC) and mini-laparotomy cholecystectomy (MLC) are used for the management of cholelithiasis. Objective: Objective of present work was to compare post operative c...