Study of effect of rational hyperoxia in perioperative period on rate of surgical site infection
Journal Title: Medpulse International Journal of Surgery - Year 2019, Vol 9, Issue 1
Abstract
Background: Oxygen supplemented at a concentration higher than 40–50 % for at least 2 h perioperatively is expected to reduce surgical site infections (SSI). Supplemental perioperative oxygen has been variously reported to halve or double the risk of surgical wound infection. Objectives: To study the effect of rational hyperoxia in perioperative period on rate of surgical site infection. Material and Methods: It was a prospective randomized control trial, with total sampel of 537. Sample was divided into clean wound of class 1 and contaminated wound of class 2. Further subdivided into hyperoxic (study) and normoxic (control) groups. Results: Out of a total of 537 patients, 335 patients were male and 202 patients were females. Male to female ratio was 1.67:1. Excision of swelling (79) was most common surgery among class 1 and primary suturing (85) was seen as most common surgery in class 2. 33.71% of patients in control group and15.75% patients in study group had SSI. Over al risk difference, attributable risk% and relative risk was 0.178, 53.13% and 2.13 respectively. Most common organism isolated from the SSI wounds in this study was pseudomonas followed by Acinetobacter suggesting hospital acquired cross infections and hence a need for more stringent asepsis protocols. No adverse event pertaining to hyperoxia such as nausea, vomiting and pulmonary complication were observed during the study. Conclusions: Overall rate of SSI for clean and clean contaminated surgeries of present study is comparable with rate of SSIs in other Indian studies, but is more than the rate of SSI for clean and clean-contaminated surgeries in other developing countries.
Authors and Affiliations
Mihir K Shah, Divyang Chavda
Keywords
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- EP ID EP471560
- DOI 10.26611/106916
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