Study of effects of Epigallocatectin-gallate (EGCG) on lipid profile and thereby cardiovascular risk
Journal Title: Medpulse International Journal of Biochemistry - Year 2018, Vol 8, Issue 2
Abstract
Background: Nowadays use of green tea has been increasing worldwide due to the beneficial effects it has on cardiovascular system. The beneficial effects of green tea can be attributed to the presence of various catectins especially Epigallocatectin-gallate (EGCG) which by number of mechanisms has protective effect on our body. Objective: This study was designed to study the effects of EGCG present in green tea on Lipid profile in volunteers from Gotri, Vadodara. The lipid lowering effect of green tea and thereby reduction in cardiovascular risk was studied. Methods: 50 men over 40 years of age surveyed on their living habits were selected and divided in two random groups of 25 each. A 12-week trial was performed, in which one group was given 5 cups of green tea per daywhereas second group was given 10 cups per day. The subjects were instructed to maintain their usual dietary intake and normal physical activity. Results: Increased consumption of green tea was found to be linked with decreased concentrations of Serum total cholesterol (p value <0.0001), Serum TG (p<0.0001), and Serum LDL concentration (p< 0.0001) and an increase in Serum HDL concentration (p< 0.0001). Conclusion: From the above findings, in this study the effect of EGCG present in green tea on lipid parameters resulting in significant decrease in total cholesterol, serum triglycerides and Serum LDL where as a significant increase in levels of Serum HDL shows that regular consumption of green tea is protective against cardiovascular diseases.
Authors and Affiliations
Asutosh P Chauhan
Keywords
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- EP ID EP442164
- DOI 10.26611/10028210
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